Recombinant AAV (rAAV) manufacturing is composed of four main components which include a rep/cap plasmid, a helper plasmid, a transgene plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method.
In stock, royalty-free, helper plasmid solution for recombinant AAV manufacturing.
In stock, royalty-free, helper plasmid solution for recombinant AAV manufacturing.
Our rep/cap plasmids provide the appropriate packaging functions for AAV-based gene therapeutics.
Our ITR reporter plasmids and cloning vectors are available for AAV-based gene therapeutics.
Aldevron, a global leader in the custom development and manufacture of plasmid DNA, RNA, and proteins for the biotech industry, signed a licensing...
Acquisition combines Aldevron's leadership in GMP manufacturing with Nature Tech's portfolio of proprietary technologies. Aldevron has acquired...
Aldevron is now offering its pALD-HELP, an off-the-shelf product supporting AAV viral vector manufacturing, in its proprietary GMP-Source® (GMP-S)...
AAV ITRs versus Transposon ITRs Inverted Terminal Repeats (ITRs) are DNA sequences flanking the transgene of interest to signal incorporation into...
Why E. coli rocks Commonly, when a person hears about Escherichia coli (E. coli), the news is negative. But it’s only a specific strain of E. coli...
Overcoming challenges, increasing yields In efforts to bring the next-generation of plasmid technology to the cell and gene therapy space, Aldevron...
