pALD-AAV System

pALD-AAV System Overview

Recombinant AAV (rAAV) manufacturing is composed of four main components which include a rep/cap plasmid, a helper plasmid, a transgene plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method.

Benefits of pALD-AAV

  • Royalty free, including for commercial products
  • Kanamycin resistance
  • Consistent, reliable supply
  • Immediately available at research grade
pALD AAV System Process Illustration

pALD-HELP Plasmid

In stock, royalty-free, helper plasmid solution for recombinant AAV manufacturing.

Learn More

pALD-X80 Plasmid

In stock, royalty-free, helper plasmid solution for recombinant AAV manufacturing.

Learn More

Rep/Cap Plasmids

Our rep/cap plasmids provide the appropriate packaging functions for AAV-based gene therapeutics.

Learn more

ITR Expression Plasmids

Our ITR reporter plasmids and cloning vectors are available for AAV-based gene therapeutics.

Learn More

Related News

Aldevron Acquires Nature Technology Corporation

Acquisition combines Aldevron's leadership in GMP manufacturing with Nature Tech's portfolio of proprietary technologies. Aldevron has acquired...

Aldevron Now Offering Its pALD-Help Plasmid for Viral Vector Production in GMP-Source® Quality Level

Aldevron is now offering its pALD-HELP, an off-the-shelf product supporting AAV viral vector manufacturing, in its proprietary GMP-Source® (GMP-S)...

Aldevron Now Offering pALD-HELP Plasmids for Viral Vector Production

Aldevron announced today it is now offering pALD-HELP to support AAV viral vector manufacturing. This additional Ad helper plasmid is immediately...

Related Blog Posts

A Focus on Analytics, for RNA and Beyond

Driving innovation of industry tools Analytical innovation is often overlooked in discussions of biotechnology product development and manufacturing...

Webinar on Demand: Advanced Plasmid Technology – Improving Safety and Performance

Nanoplasmid™ Vectors: The Power of Small In cell and gene therapies, delivery is a critical factor. Regardless of your modality, optimizing payload,...

A Complete Suite of rAAV Constructs

New ITR Cloning and Reporter Constructs Now Available By Jeff Briganti, Senior Director, Global Strategic Marketing Manufacturing standardization for...