pALD-AAV System

pALD-AAV System Overview

Recombinant AAV (rAAV) manufacturing is composed of four main components which include a rep/cap plasmid, a helper plasmid, a transgene plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method.

Benefits of pALD-AAV

  • Royalty free, including for commercial products
  • Kanamycin resistance
  • Consistent, reliable supply
  • Immediately available at research grade
pALD AAV System Process Illustration

pALD-HELP Plasmid

In stock, royalty-free, helper plasmid solution for recombinant AAV manufacturing.

Learn More

pALD-X80 Plasmid

In stock, royalty-free, helper plasmid solution for recombinant AAV manufacturing.

Learn More

Rep/Cap Plasmids

Our rep/cap plasmids provide the appropriate packaging functions for AAV-based gene therapeutics.

Learn more

ITR Expression Plasmids

Our ITR reporter plasmids and cloning vectors are available for AAV-based gene therapeutics.

Learn More

Related News

Aldevron Signs Licensing Agreement With Genentech

Aldevron, a global leader in the custom development and manufacture of plasmid DNA, RNA, and proteins for the biotech industry, signed a licensing...

Aldevron Acquires Nature Technology Corporation

Acquisition combines Aldevron's leadership in GMP manufacturing with Nature Tech's portfolio of proprietary technologies. Aldevron has acquired...

Aldevron Now Offering Its pALD-Help Plasmid for Viral Vector Production in GMP-Source® Quality Level

Aldevron is now offering its pALD-HELP, an off-the-shelf product supporting AAV viral vector manufacturing, in its proprietary GMP-Source® (GMP-S)...

Related Blog Posts

An ITR Faceoff

AAV ITRs versus Transposon ITRs Inverted Terminal Repeats (ITRs) are DNA sequences flanking the transgene of interest to signal incorporation into...

Rocking in the E. World

Why E. coli rocks Commonly, when a person hears about Escherichia coli (E. coli), the news is negative. But it’s only a specific strain of E. coli...

Apply for the Nanoplasmidᵀᴹ AAV Construct Giveaway

Overcoming challenges, increasing yields In efforts to bring the next-generation of plasmid technology to the cell and gene therapy space, Aldevron...