Custom Manufacturing Services

Advancing Every Day

Aldevron is a leading, global Contract Development and Manufacturing Organization (CDMO). Actually, we are more than a CDMO, inventing and implementing solutions to help advance our partner’s life-altering therapies. We have served thousands of clients as partner-of-choice providing high-quality plasmid DNA, RNA, and proteins for research, therapeutics (GMP-Source™ & full GMP), and diagnostics.

Traditional Plasmid DNA Production

Aldevron manufactures plasmid DNA for research, preclinical, clinical, and commercial applications scaled to fit projects of any size and scope. Whether you're looking for research grade, GMP, or our exclusive GMP-Source™ plasmids, we've developed unsurpassed expertise in plasmid manufacturing.

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Nanoplasmid™ DNA Production & Retrofit

The Nanoplasmid Vector System (<500 bp backbone) encompasses all the performance benefits of mini-circles while improving upon the manufacturing yields of traditional plasmids.

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mRNA Drug Substance and Drug Product Production

Aldevron has been a leader the mRNA manufacturing space since 2017, having released >80 GMP batches of RNA drug substance and supporting numerous IND submissions. More recently, Aldevron has expanded capabilities to provide end-to-end drug product manufacturing.

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Protein/Enzyme Production

Aldevron provides a wide range of protein services including host cell optimization, expression screening, process development, contract production, assay design and more. Our proteins are available for research, molecular diagnostic, and therapeutic (full GMP) applications.

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Storage & Stability

As an added service, Aldevron offers Aldevron Storage Distribution Services (ASDS) which provides a secure, monitored facility for storage and shipment of research-grade, GMP-Source, and GMP materials. Aldevron also offers stability testing tailored to your timeline, needs and budget.

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CRISPR Ribonucleoprotein (RNP) Manufacturing*

Streamline your CRISPR reagents into therapies. Working with your unique guide RNAs (gRNAs), we’ve defined optimal conditions for complexing, characterizing, and storing CRISPR RNPs created with Aldevron in-stock or custom manufactured research and GMP-grade CRISPR/Cas9 proteins.

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*Aldevron provides RNPs only to customers who are duly licensed, including to make and have made RNPs, for their intended use.