CRISPR/Cas9 Gene Editing Tools

From research through clinical development

Aldevron provides a one-vendor strategy for preclinical through GMP gene editing nucleases. Using Cas9 in protein form provides many benefits, including reduced off-target effects, immediate intracellular activity and controlled dosage capabilities. Aldevron gene editing nucleases are available as catalog products in standard formulations and can be custom manufactured to meet your exact needs.

Our enzymes are engineered to be used in a variety of applications including electroporation, transfection and microinjection. We provide several options for research, GMP-Source® (GMP-S) and GMP quality grades, providing a seamless transition from research through clinical stages of development. 


In-stock Products: CRISPR-Associated Nucleases

Standard formulations for immediate delivery. Includes SpyFiTM Cas9 Nuclease, sNLS-SpCas9-sNLS and sNLS-AsCas12a-sNLS. Custom formulations on request.

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SpyFiTM Cas9 Nuclease

From basic research to clinical applications, our SpyFi Cas9 Nuclease delivers greater editing efficiency and reduced off-target effects without loss of on-target activity.

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sNLS-SpCas9-sNLS Nuclease

Aldevron offers Cas9 nucleases for discovery, preclinical and clinical uses under our Research Grade, GMP-Source and GMP quality levels.

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Custom Manufactured CRISPR-Associated Nucleases

Aldevron can manufacture custom and unique configurations such as dCas9 fusions, nickases and variants according to your designs.

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Not Sure Which Option is Best?

Contact us for more information about what can work best for you.

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