sNLS-SpCas9-sNLS Nuclease

A simple solution from R&D to clinical material

Aldevron provides research grade Cas9 nucleases for use in development work as well as standard GMP products for clinical studies. The concentration for these products is 10 mg/mL, dispensed in the following sizes:


Functional Performance

Manufacturing and Quality Control

Download CoAs to See QC Specifications

To download your CoAs, please provide your contact information below. We do not share your information with any third parties.

sNLS-SpCas9-sNLS Nuclease Quality Control Specifications
Purity, RP-HPLC ≥95%
Purity, SDS-PAGE ≥95%
Aggregation ≤5% aggregate
Concentration 10.0 mg/mL +/- 10%
Endotoxin ≤ 10 EU/mg
Residual DNase < LOQ
Residual RNase < LOQ
Appearance Clear, colorless
Residual Host Protein ≤ 200 ng/mL
Residual Host GenomicDNA < 1% (w/w)
Activity Assay, in vitro ≥80% of uncut reference DNA converted to cleavage products
Bioburden < 2 CFU/Sample
Mycoplasma Negative for the presence of Mycoplasma


Ordering Information

Product Small Size Catalog Number Large Sizes Catalog Number
SpCas9 Nuclease 0.25MG 9212-0.25MG 5MG 9212-5MG
GMP-Manufactured Nucleases
SpCas9 Nuclease - GMP 1MG 9211-0.1ML 10MG 9211-1ML

region na1
portalId 1769030
formId e5fad561-a320-47dd-9443-e47d9821f193
target Services-hubspot-form
General Data Protection Regulation (GDPR) information

Aldevron complies with the requirements of the General Data Protection Regulation (GDPR).

What We Collect
Information collected on this form will be used to contact you (by email or telephone) about your chosen areas of interest, or previous or proposed business transactions.

How to withdraw your consent
You can choose whether or not to receive future marketing emails using the opt-in checkbox in the form. You can unsubscribe from future email contacts, or if you wish for all your information to be withdrawn, visit our GDPR web page to learn about the process.

Sharing of Information
We will not sell or otherwise transfer your data to a third party for monetary consideration. We will not disclose information about you to a non-affiliated third party except at your request or if you consent to the disclosure.

Information Automatically Collected
Aldevron automatically tracks certain information based on your behavior on our site, using tools such as Google Analytics. This information may include websites or search engines that referred you to our site, what browser you are using, and your IP address. We use this information to analyze how our visitors use the site.

Learn more about our privacy policies