Product Name | Product Description |
---|---|
Guanylyltransferase |
Guanyltransferase (GT), also known as Vaccinia Capping Enzyme (VCE), catalyzes addition of 7-methylguanylate cap structures (Cap 0) to the 5’ end of RNA in three steps: |
2’-O-Methyltransferase |
2'-O-Methyltransferase adds a methyl group to the 2'-OH of the first nucleotide adjacent to the m7Gppp5'N cap. 2'-O-Methyltransferase utilizes |
Enzymes for mRNA Production
Our in vitro transcription (IVT) enzymes are qualified both by activity assays and functionally for RNA synthesis and can be custom manufactured to meet your specific project requirements from milligram to multigram scale. View the table below for a summary of our IVT enzymes.
Product Name | Product Description |
---|---|
T7 RNA Polymerase |
T7 RNA Polymerase catalyzes synthesis of RNA in the presence of a DNA template containing the T7 phage promoter. |
Inorganic Pyrophosphatase |
Inorganic Pyrophosphatase catalyzes hydrolysis of inorganic pyrophosphate, producing two molecules of phosphate. |
Ribonuclease Inhibitor |
Ribonuclease Inhibitor is a potent, noncompetitive inhibitor of pancreatic-type ribonucleases including ribonucleases A, B and C. |
DNase I |
DNase I nonspecifically cleaves single- or double-stranded DNA, producing di-, tri- and oligonucleotide products. DNase I is free of detectable ribonuclease activity. |
Product Name | Product Description |
---|---|
Poly(A) Polymerase |
Poly(A) Polymerase catalyzes addition of AMP from ATP to the 3' end of RNA in a template-independent manner. |
IVT Enzymes | Catalog Number | Small Size | Large Sizes |
2’-O-Methyltransferase | 9130 | 1450 mcg | 3400 mcg |
Guanylyltransferase | 9131 | 300 mcg | 1750 mcg |
Inorganic Pyrophosphatase | 9132 | 350 mcg | 1870 mcg |
Poly(A) Polymerase | 9133 | 430 mcg | 3000 mcg |
Ribonuclease Inhibitor | 9134 | 180 mcg / 660 mcg | 2500 mcg |
T7 RNA Polymerase | 9135 | 130 mcg | 2000 mcg |
DNase I | 9136 | 70 mcg | 500 mcg |
Interested in a sample, pricing or cGMP manufacturing of IVT enzymes? Contact our Protein Team