References

Date Reference Products
October 2016 Königer et al (2016), ' Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA', Nature Microbiology GM-0501
GM-0505
GM-0503
GM-0509
GM-0512
July 2016 Belvedere et al (2016), 'Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of formyl peptide receptor pathway', Scientific reports GM-0601
July 2016 Simiele et al (2016), 'Epigenetic regulation of the formyl peptide receptor 2 gene', Biochemica et Biophyscia Acta GM-0601
May 2016 Muenzner et al (2016), 'Uropathogenic E.coli exploit CEA to promote colonisation of the urogenital tract mucosa', PLos GM-0501
GM-0505
GM-0509
May 2016 Liebler et al (2016), 'Towards a biofunctionalised vascular prosthesis: immune cell trapping via a growth factor receptor', J Tissue Eng Regen Med GM-1006
GM-1007
March 2016 Fontana et al, 'Analysis of a spontaneous non-motile and avirulent mutant shows that FLiM is required for full endoflagella assembly in Leptospira interrogans' PLoS ONE  
March 2016 Baumert et al, 'Hepatitis C virus cell entry: a target for novel antiviral strategies to address limitations of direct acting antivirals', Hepatol Int  
March 2016 Schurmans et al, 'Specific expression and function of inositol 1,4,5-triphosphate 3-kinase C (ITPKC) in wild type and knock-out mice, Advances in Biological regulation (2016) 1-10  
January 2016 Schmohl et al (2016), Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk, Experimental Haematology  
August 2015 (2015) 10th international Luebeck conference on the pathophysiology and pharmacology of erythropoietin and other hemopoietic growth factors. Am. J. Hematol., 90: E154–E180  
July 2015 Buettner et al, 9.O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. Nature Communications, 6:7673  
July 2015 Tchoupa et al (2015), Outer membrane protein P1 is the CEACAM-binding adhesin of Haemophilus Influenzae. Molecular Microbiology  
April 2015 Tawar et al (2015), Claudins and pathogenesis of viral infection. Cell and Developmental Biology, 42:39-46  
March 2015 Mailly et al (2015), Clearance of persistent hepatitis C virus infection in humanised mice using claudin-1-targeting monoclonal antibody. Nature GM-1110
GM-1111
February 2015 Linch et al (2015), OX40 agonists and combination immunotherapy: putting the pedal to the metal. Frontiers in Oncology 5, 34.  
February 2015 Maxwell P, et al. (2015). Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. Br. J. Haematol 168(3):429-42 GM-1201
GM-1202
December 2014 Belvedere et al (2014), 'Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells', BMC Cancer; 14:961 GM-0601
December 2014 Dveksler et al (2014) Induction and activation of latent TGF-beta1 is carried out by two distinct domains of Pregnancy-specific Glycoprotein 1. The journal od biological chemistry  
December 2014 Pierdomenico et al (2014) microRNA-181b regulates ALX/FPR2 expression and proresolution signaling in human macrophages. The journal of biological chemistry GM-0601
September 2014 Isik et al (2014): Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL  
August 2014 Filipovic et al. (2014) Anti-Nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. Breast cancer res treat. Aug 2014  
June 2014 Lombardo et al (2014): Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymeal transition in MCF7 breast cancer cells  
June 2014 Denizot J et al (2014): Diet.Induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia Coli colonisation GM-0509
May 2014 Goodrich A. et al (2014): Influence of a dual-injection regimen, plerixafor and CXCR4 on in utero hematopoietic stem cell transplantation and engraftment with use of the sheep model GM-0805
May 2014 Xiao et al (2014): Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepititis C  
February 2014 Zona et al (2014): CD81-Receptor associations - impact for hepatitis C virus entry and antiviral therapies  
January 2014 Nadkarni S et al (2104): Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression. Circ Res. 114: 242-248, doi: 10.1161/CIRCRESAHA.114.301374 GM-0601
January 2014 Peitsch C et al (2014): Activation of Influenza A Viruses by Host Proteases from Swine Airway Epithelium. J. Virol. 88/1: 282-291. 10.1128/JVI.01635-13  
December 2013 Curti et a (2013): OX40 is a potent immune-stimulating target in late-stage cancer patients, Cancer Res, 73:7189-7198  
December 2013 Neumann D et al (2013): Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation. Poster 2175 presented at the 55th ASH Meeting, New Orleans 7-10 Dec 2013. GM-1202
November 2013 Hutchings CJ et al (2013): Monoclonal anti-β 1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment. mAbs 6/1, 10.4161/mabs.27226  
November 2013 He HQ et al (2103): Structural Determinants for the Interaction of Formyl Peptide Receptor 2 with Peptide Ligands. The Journal of Biological Chemistry, 289: 2295-2306. 10.1074/jbc.M113.509216 GM-0601
October 2013 Liu et al (2013), 'Analysis of LGR4 receptor distribution in human and mouse tissues' PLOS One, 8:10  
October 2013 Patel PC et al (2013): Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties. J Biol Chem 288/41: 29654-69. 10.1074/jbc.M113.504639 GM-0505
October 2013 Natoli A et al (2103): Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs. Int. J. Cancer, 133: 1945–1954. doi: 10.1002/ijc.28189 GM-0104
September 2013 Rothmeier E et al (2013): Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection. PLoS Pathog 9(9): e1003598. doi:10.1371/journal.ppat.1003598  
September 2013 Fofana I et al (2013): Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies. J Virol.; 87(18): 10405-10. doi: 10.1128/JVI.01691-13 GM-1110
GM-1111
GM-1112
August 2013 Klaile E et al (2013): Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons. Respiratory Res, 14:85 doi:10.1186/1465-9921-14-85  
August 2013 Denzau S et al (2013): Ontogenetic development of magnetic compass orientation in domestic chickens (Gallus gallus). J Exp Biol 216, 3143-3147.10.1242/jeb.088815  
July 2013 Johswich KO et al (2013): In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa. PLoS Pathog 9/7: e1003509. 10.1371/journal.ppat.1003509 GM-0505
July 2013 Harbuzariu A et al (2013): CD34 affinity pheresis attenuates a surge among circulating progenitor cells following vascular injury. J Vascular Surgery, doi: 10.1016/j.jvs.2013.05.043 GM-0805
June 2013 Miyahara T et al (2013): D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury. FASEB J. 27/6:2220-32. 10.1096/fj.12-225615. GM-0601
June 2013 Meyer D et al (2013): Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. Biochem J. 452/2: 331-43. 10.1042/BJ20130101  
June 2013 Dalli J et al (2103): Proresolving and Tissue-Protective Actions of Annexin A1–Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor. The Journal of Immunology 190/12: 6478-6487. 10.4049/jimmunol.1203000 GM-0601
June 2013 Bontjer I et al (2013): Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers. PLOS ONE 10.1371/journal.pone.0067484  
May 2013 Witzens-Harig M et al (2103): Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6. Blood 121/22: 4493-503. 10.1182/blood-2012-05-429415 GM-0509
May 2013 Scheiter M et al (2013): Proteome analysis of distinct developmental stages of human natural killer (NK) cells. Mol Cell Proteomics 12/5: 1099-114. 10.1074/mcp.M112.024596 GM-0908
May 2013 Fofana I et al (2013): A Novel Monoclonal Anti-CD81 Antibody Produced by Genetic Immunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission. PLoS ONE 8(5): e64221. doi:10.1371/journal.pone.0064221 GM-1113
May 2013 Denzau S et al (2013): Different responses of two strains of chickens to different training procedures for magnetic directions. Animal cognition, 16/3: 395-403  
March 2013 Palin AC et al (2013): Human Neonatal Naive CD4+ T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a. J Immunol 190/6: 2682-2691, 10.4049/jimmunol.1202534  
March 2013 Meyer D et al (2013): Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. Biochem. J. 452/2: 331–343, 10.1042/BJ20130101  
February 2013 de Jong MF et al (2013): Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response. mBio 4/1, 10.1128/mBio.00418-12  
January 2013 Zhang et al (2013): Role of CEACAM1 and CEACAM20 in an In Vitro Model of Prostate Morphogenesis. PLOS ONE 10.1371/journal.pone.0053359  
December 2012 Zahid MN et al (2012): The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination. Hepatology. doi: 10.1002/hep.26097  
December 2012 Lotfi R et al (2102): Necrosis-Associated Factors (DAMPs) Including S100A4 Used to Pulse Dendritic Cells (DCs) Induce Regulatory T cells. J Cell Sci Ther 3:134. doi:10.4172/2157-7013.1000134  
November 2012 Kobayashi M et al (2012): Carcinoembryonic antigen-related cell adhesion molecules assurrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107/10: 1745-53. 10.1038/bjc.2012.422 GM-0508
GM-0515
November 2012 Dakin SG et al (2102): Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. PLoS One 7/11: e48978. 10.1371/journal.pone.0048978 GM-0601
October 2012 Lotfi R et al (2012): Nekrose-assoziierte Faktoren (DAMPs) beschleunigen nicht nur die Tumorproliferation sondern beeinflussen auch die adaptive Immunantwort. Bedeutung von S100A4 im Tumormilieu. Abstract of the annual meeting of the DGHO, Stuttgart 19.-23.10.2012 GM-0908
September 2012 Darrabie M et al (2012): Exposing cardiomyocytes to subclinical concentrations of doxorubicin rapidly reduces their creatine transport. American Journal of Physiology - Heart and Circulatory Physiology, 303/H539-H548, 10.1152/ajpheart.00108.2012  
September 2012 Bizzarro V et al (2012): Annexin A1 N-Terminal Derived Peptide Ac2-26 Stimulates Fibroblast Migration in High Glucose Conditions. PLoS ONE, 7(9), Sep 2012 GM-0601
August 2012 Kemper et al (2012), 'Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells', Stem cells express  
August 2012 Norling LV et al (2012): Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol.; 32(8): 1970-8. GM-0601
July 2012 Bena S et al (2012): Annexin A1 Interaction with the FPR2/ALX Receptor. Identification of distinct domains and downstream associated signaling. J Biol Chem, 287(29): 24690–24697. GM-0601
June 2012 Voges M et al (2012): Extracellular IgC2 Constant Domains of CEACAMs Mediate PI3K Sensitivity during Uptake of Pathogens. PLoS One. 2012; 7(6): e39908. GM-0505
June 2012 Klarenbeck A et al (2012): Targeting chemokines and chemokine receptors with antibodies. Drug Discovery Today: Technologies, http://dx.doi.org/10.1016/j.ddtec.2012.05.003  
May 2012 Peng L et al (2012): The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA. PLoS One. 2012; 7(5): e36412. GM-0503
May 2012 Partyka K et al (2012): Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification. J Proteome Res. 11/5: 2904-11. 10.1021/pr2012736 GM-0503
May 2012 Drukker M et al (2012): Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol. 30/6: 531-42. 10.1038/nbt.2239 GM-0503
April 2012 Kammerer R et al (2012): Loss of the mammal-specific tectorial membrane component CEA cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies J. Biol. Chem., doi:10.1074/jbc.M111.320481 GM-0518
April 2012 Fagerhol MK et al (2102): Large molecular size EDTA-resistant complexes containing S100A12, ERAC, in serum during inflammatory conditions. Scandinavian Journal of Clinical & Laboratory Investigation 72/2: 129-136, 10.3109/00365513.2011.643819  
March 2012 Talekar A (2012): Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment. PLoS One. 2012; 7(3): e30538.  
March 2012 Melchers M et al (2012): Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses. J Virol. 86(5):2488-500. doi: 10.1128/JVI.06259-1  
March 2012 Christianson GJ et al (2012): Monoclonal antibodies directed against human FcRn and their applications. MAbs Mar 1;4(2). PMID 22453095 GM-0808
GM-0809
February 2012 Haines DS et al (2012): Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking. Mol Cell Proteomics.10.1074/mcp.M111.016444 GM-0804
February 2012 Dalli J et al (2012): Annexin A1 N-Terminal Derived Peptide Ac2-26 Exerts Chemokinetic Effects on Human Neutrophils. Frontiers in Pharmacology, 3: 28, doi:10.3389/fphar.2012.00028 GM-0601
February 2012 Dakin SG et al (2102): Macrophage sub-populations and the lipoxin A4 receptor implicate active inflammation during equine tendon repair.PLoS One 7/2: e32333. 10.1371/journal.pone.0032333 GM-0601
January 2012 Sarantis H and SD Gray-Owen (2012): Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae. Infect Immun. 80/1: 345-58. 10.1128/IAI.05702-11 GM-0505
GM-0509
GM-0511
GM-0512
January 2012 Pesce L et al (2012): TSH Regulates Pendrin Membrane Abundance and Enhances Iodide Efflux in Thyroid Cells. Endocrinology, 153(1): 512–521. 10.1210/en.2011-1548  
December 2011 Zhou J et al (2011): Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 23/9: 172. 10.1186/1477-7819-9-172 GM-0508
November 2011 Simiele F et al (2011): Transcriptional regulation of the human FPR2/ALX gene: evidence of a heritable genetic variant that impairs promoter activity. FASEB 11-198069. GM-0601
November 2011 Burden CS et al (2011): A monolith purification process for virus-like particles from yeast homogenate. Journal of Chromatography B, doi:10.1016/j.jchromb.2011.10.044  
November 2011 Hermann RJ et al (2011): Characterization and use of a rabbit-anti-mouse VPAC1 antibody by flow cytometry. Journal of Immunological Methods, doi:10.1016/j.jim.2011.10.009  
October 2011 Balenga NAB et al (2011): GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. Cell Res. 21(10): 1452–1469  
October 2011 Weinberg A et al (2011): Science gone translational: the OX40 agonist story. Immunological Reviews 244/1: 218-231  
August 2011 de Lau W et al (2011): Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476/293, doi:10.1038/ nature10337  
July 2011 Queval CJ et al (2011): Role of Src Kinases in Mobilization of Glycosylphosphatidylinositol-Anchored Decay-Accelerating Factor by Dr Fimbria-Positive Adhering Bacteria. Infect. Immun. 79/7: 2519-2534. 10.1128/IAI.01052-1 GM-0505
July 2011 Graham SA et al (2011): Identification of neutrophil granule glycoproteins as Lewis(x)-containing ligands cleared by the scavenger receptor C-type lectin. J Biol Chem 286/27: 24336-49. 10.1074/jbc.M111.244772 GM-0504
June 2011 van Montfort T et al (2011): A Chimeric HIV-1 Envelope Glycoprotein Trimer with an Embedded Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Domain Induces Enhanced Antibody and T Cell Responses. JBC, 286, 22250-22261  
June 2011 Moreland AJ et al (2011): Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques. BMC Genomics 12/295. 10.1186/1471-2164-12-295 GM-0504
June 2011 Green LR et al (2011): Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells. Infect Immun 79/6:2241-9. 10.1128/IAI.01354-10 GM-0505
June 2011 Denizot J et al (2012): Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients. Inflamm Bowel Dis, 18: 294–304. 10.1002/ibd.21787 GM-0509
May 2011 Niessner C et al (2011): Avian Ultraviolet/Violet Cones Identified as Probable Magnetoreceptors. PLoS One. 2011; 6(5): e20091.  
May 2011 Liévin-Le Moal V et al (2011): Apical expression of human full-length hCEACAM1-4L protein renders the Madin Darby Canine Kidney cells responsive to lipopolysaccharide leading to TLR4-dependent Erk1/2 and p38 MAPK signalling. Cellular Microbiology, 13: 764–785. 10.1111/j.1462-5822.2011.01575.x GM-0505
May 2011 Vomhof-DeKrey EE et al (2011):Vasoactive intestinal peptide receptor 1 is downregulated during expansion of antigen-specific CD8 T cells following primary and secondary Listeria monocytogenes infections. J Neuroimmunol, 234/1–2: 40–48, 10.1016/j.jneuroim.2011.02.002  
April 2011 Deuquet J et al (2011): Hyaline Fibromatosis Syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors. EMBO Mol Med. 2011 April; 3(4): 208–221. 10.1002/emmm.201100124  
April 2011 Brancaleone V et al (2011): Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature. JImmunol 186/8, 4905-4914 GM-0601
April 2011 Zaremba A, Schmuecker U and Esche H (2011): Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway.Virology Journal 2011, 8:192  
March 2011 Seizer P et al (2011): Disrupting the Extracellular Matrix Metalloproteinase Inducer–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion. ATVBAHA, 10.1161/ATVBAHA.111.225771  
March 2011 Seizer P et al (2011): Disrupting the EMMPRIN (CD147)–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion. Arteriosclerosis, Thrombosis, and Vascular Biology, 31: 1377-1386. 10.1161/ATVBAHA.111.225771  
March 2011 Porotto M et al (2011): Synthetic protocells interact with viral nanomachinery and inactivate pathogenic human virus. PLoS One. 2011; 6(3): e16874.  
January 2011 Kuespert K et al (2011): Neisseria meningitidis has two independent modes of recognizing its human receptor CEACAM1. PLoS One. 2011; 6(1): e14609. GM-0505
GM-0511
December 2010 Hutchings CJ et al (2010): Therapeutic antibodies directed at G protein-coupled receptors. mAbs 2/6, 594-606.  
December 2010 Legrand F et al (2010): Human Eosinophils Exert TNF-α and Granzyme A-Mediated Tumoricidal Activity toward Colon Carcinoma Cells. JImmunol 185/12, 7443-7451  
November 2010 Zeisel M et al (2010): Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. J Hepatol, doi:10.1016/j.jhep.2010.10.014  
November 2010 De Santo C et al (2010): Invariant NKT cells modulate the suppressive activity of Serum Amyloid A-differentiated IL-10-secreting neutrophils. Nat Immunol.; 11(11): 1039–1046. GM-0601
October 2010 Spurr L et al (2010): Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets. International Immunopharmacology, doi:10.1016/j.intimp.2010.10.006 GM-0601
October 2010 Rolhion N et al (2010): Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion. Gut, 59/10: 1355-6 GM-0509
October 2010 Weibel R et al (2010): Development of Standard Test Procedures for Quantifying Carry Over from Fixed Pipetting Tips in Liquid-Handling Systems. J Ass Lab Auto, 15/5: 369-378  
October 2010 Iten M et al (2010): Reduction of Carry Over in Liquid-Handling Systems With a Decontamination Step Integrated in the Washing Procedure. J Ass Lab Auto, 15/5: 379-389  
September 2010 Xianfeng Chen, Angela Shaulov Kask, et al (2010) Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays, Journal of Controlled Release, Volume 148, Issue 3, 20 December 2010, Pages 327-333, ISSN 0168-3659, DOI: 10.1016/j.jconrel.2010.09.001.  
September 2010 VanDuijn M et al (2010): Immune Responses Are Characterized by Specific Shared Immunoglobulin Peptides That Can Be Detected by Proteomic Techniques. JBC 285, 29247-29253.  
September 2010 Fofana I et al (2010): Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastoenterology (10.1053/j.gastro.2010.05.073).  
September 2010 Angela Shaulov Kask, Xianfeng Chen, et al (2010): DNA vaccine delivery by densely-packed and short microprojection arrays to skin protects against vaginal HSV-2 challenge, Vaccine, Volume 28, Issue 47, 3 November 2010, Pages 7483-7491, ISSN 0264-410X, DOI: 10.1016/j.vaccine.2010.09.014.  
August 2010 Kanderova V et al (2010): Aberrantly expressed CEACAM6 is involved in the signaling leading to apoptosis of acute lymphoblastic leukemia cells. Exp Hem 38/8, 653-660. GM-0509
July 2010 Ha CT et al (2010): Human Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Has a Potential Role in Placental Vascular Morphogenesis. Biol Reprod.; 83(1): 27–35  
June 2010 Ortner E et al (2010): Sensitive and selective detection of free FXIII activation peptide: a potential marker of acute thrombotic events. Blood 115/24, 5089-5096  
June 2010 Catusse J et al (2010): Attenuation of CXCR4 responses by CCL18 in acute lymphocytic leukemia B cells. J. Cell. Physiol., 225: 792–800. 10.1002/jcp.22284  
April 2010 Krieger SE et al (2010): Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-Claudin-1 associates. Hepatology, 51/4:1144-57  
April 2010 Betts AM et al (2010): The Application of Target Information and Preclinical Pharmacokinetic/Pharmacodynamic Modeling in Predicting Clinical Doses of a Dickkopf-1 Antibody for Osteoporosis. JPet, 333/1, 2-13  
March 2010 Abrami L et al (2010): Endocytosis of the Anthrax toxin is mediated by Clathrin, Actin and unconventional adaptors. PLoS Pathog. 2010 March; 6(3): e1000792.  
January 2010 Singer B et al (2010): Deregulation of the CEACAM Expression Pattern Causes Undifferentiated Cell Growth in Human Lung Adenocarcinoma Cells. PLoS One. 2010; 5(1): e8747 GM-0508
GM-0509
December 2009 Ramkumar P (2009): Generation and characterization of novel monoclonal antibodies recognizing UBXD1. Hybridoma 28(6):459-62. doi: 10.1089/hyb.2009.0035. GM-0803
GM-0804
September 2009 Carvalho, FA et al (2009): Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM. JEM, 206/10: 2179-2189. GM-0509
August 2009 Gross JC et al (2009): E-cadherin Surface Levels in Epithelial Growth Factor-stimulated Cells Depend on Adherens Junction Protein Shrew-1. MBoC 20/15: 3598-3607  
July 2009 Yue T et al (2009): The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. Mol Cell Proteomics. 8(7): 1697-707. GM-0501
GM-0505
GM-0508
GM-0509
July 2009 Bratke et al (2009): Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4+ T cells by down-regulation of granzyme B. Immunology. 127/3: 338–344 GM-0202
July 2009 Adler H et al (2009): Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1. PLoS ONE 4/7  
May 2009 Porotto M et al (2009): Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy. J Virol., 83(10): 5148-55.  
May 2009 Martins V et al (2009): ATLa, an Aspirin-Triggered Lipoxin A4 Synthetic Analog, Prevents the Inflammatory and Fibrotic Effects of Bleomycin-Induced Pulmonary Fibrosis. J Immunol, 182: 5374 -5381 GM-0601
May 2009 Kang H et al (2009): Transfection of insulin-secreting cell line and rat islets by functional polymeric gene vector. Biomaterials, 30/14: 2837-2845  
March 2009 Taori V et al (2009): DNA delivery in vitro via surface release from multilayer assemblies with poly(glycoamidoamine)s. Acta Biomaterialia, 5/3: 925-933  
March 2009 Han Y et al (2009): Using DNA as drug-bioprocessing and delivery strategies. Chemical Engineering Research and Design, 87/3: 343-348  
March 2009 Latulippe D et al (2009): Elongational flow model for transmission of supercoiled plasmid DNA during membrane ultrafiltration. Journal of Membrane Science, 329/1: 201-208  
February2009 Teijeiro-Osorio D et al (2009): Chitosan/cyclodextrin nanoparticles can efficiently transfect the airway epithelium in vitro. Eur J Pharm Biopharm, 71/2: 257-263  
February 2009 Srinivasachari S et al (2009): Versatile supramolecular pDNA vehicles via "click polymerization" of beta-cyclodextrin with oligoethyleneamines. Biomaterials, 30/5: 928-938  
February 2009 Semiramoth N et al (2009): Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase -and MAPK- dependent mechanism. J Leukocyte Biol, 85, 1-12 GM-0501
GM-0509
January 2009 Guignot J et al. (2009): Human decay-accelerating factor and CEACAM receptor-mediated internalization and intracellular lifestyle of Afa/Dr diffusely adhering escherichia coli in epithelial cells. Infection and Immunity, 77/1, 517-531 GM-0505
December 2008 Polymenidou M et al. (2008): The POM Monoclonals: A comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS ONE ; 3/12: e3872.  
December 2008 Porada CD et al (2008): Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells. Exp Hematol, 36/12: 1739-1749 GM-0805
November 2008 Hooper JW, et al (2008): Immune serum produced by DNA vaccination protects hamsters against lethal respiratory challenge with Andes virus. FJ Virol., 82(3):1332-8.  
November 2008 Beaslas O et al (2008): Transcriptome response of enterocytes to dietary lipids: impact on cell architecture, signaling, and metabolism genes. Am J Physiol Gastrointest Liver Physiol, 295/5: G942-52 GM-0501
July 2008 Paulmann D et al. (2008): Hepatitis A virus protein 2B suppresses beta interferon (IFN) gene transcription by interfering with IFN regulatory factor 3 activation. J Gen Virol 89, 1593-1604  
June 2008 Thomas SN et al. (2008): Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow. J Biol Chem, 283: 15647-55. GM-0501
GM-0507
GM-0508
GM-0509
June 2008 Planaguama A et al (2008): Airway Lipoxin A4 Generation and Lipoxin A4 Receptor Expression Are Decreased in Severe Asthma. Am J Respir Crit Care Med, 178a: 574-582 GM-0601
June 2008 Nittka S et al (2008): The CEACAM1-mediated apoptosis pathway is activated by CEA and triggers dual cleavage of CEACAM1 Activation and processing of CEACAM1 during apoptosis. Oncogene 27, 3721-3728 GM-0501
May 2008 Lee HSW et al (2008): CEACAM1 Dynamics during Neisseria gonorrhoeae Suppression of CD4+ T Lymphocyte Activation. J Immunol, 180: 6827-6835 GM-0505
May 2008 Dalley D et al (2008): Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles). Tuberculosis 88/3: 235-243, doi:10.1016/j.tube.2007.11.001  
February 2008 Björkman L et al (2008): Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1. J Leukoc Biol, 83: 245-53 GM-0601
December 2007 Yoon J et al (2007): CD66b regulates adhesion and activation of human eosinophils. J Immunol, 179: 8454-62 GM-0501
GM-0512
December 2007 Zeisel M et al. (2007): Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology, 46/6:1722-31  
December 2007 Riesenberg R et al (2007): Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma. Clin Cancer Res, 13/23, 6993-7002 GM-0511
December 2007 Kilic N et al (2007): Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1. Blood, 110/13, 4223-4233 GM-0508
GM-0509
GM-0511
August 2007 Schmitter T et al (2007): Opa proteins of pathogenic neisseriae initiate Src kinase-dependent or lipid raft-mediated uptake via distinct human carcinoembryonic antigen-related cell adhesion molecule isoforms. Infect Immun, 75/8:4116-26. GM-0505
June 2007 Bonn S et al (2007): Combinatorial expression of α- and γ-protocadherins alters their presenilin-dependent processing. Mol Cell Biol, 27/11: 4121-4132  
May 2007 Morris NP et al (2007): Development and characterization of recombinant human Fc:OX40L fusion protein linked via a coiled-coil trimerization domain. Mol Immunol 44/12: 3112-3121  
May 2007 Catanese MT et al. (2007): High avidity monoclonal antibodies against human scavenger receptor class B type I efficiently block hepatitis C virus infection in the presence of HDL. J Virol, 2007 0: JVI.00193-07  
April 2007 Schreiner A et al. (2007): Junction protein Shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147. Mol Biol Cell, 18/4:1272-81  
March 2007 Vicovac L et al (2007):Carcinoembryonic Antigen and Related Molecules in Normal and Transformed Trophoblast. Placenta 28/2-3:85-96, doi:10.1016/j.placenta.2006.02.002  
February 2007 Chan CHF et al. (2007): Colorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice. PLoS ONE, 2/12: e1353 GM-0509
January 2007 Viswanathan A et al. (2007): Functional expression of N-formyl peptide receptors in human bone marrow-derived mesenchymal stem cells. Stem Cells, 25/5:1263-9 GM-0601
December 2006 Weinberg AD et al. (2006): Anti-OX40 (CD134) Administration to nonhuman primates: immunostimulatory effects and toxicokinetic study. J Immunother, 29/6: 575-585  
November 2006 Ellies D et al. (2006): Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res, 21/11:1738-49  
October 2006 D'Amour K et al (2006): Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol, 24/1: 1392-1401  
September 2006 Maraqa L. et al (2006): CEACAM: A potential novel predictor of breast cancer recurrence. AACR Meeting Abstracts 2006 : PR-8 GM-0506
September 2006 Technology Feature: 'Chain gang' delivers for hard labor. Nature Methods, 3/9: 753-762  
May 2006 Tsutsumida H et al (2006): RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells. Clin Cancer Res, 12: 2976-87 GM-0506
April 2006 Krause S et al. (2006): Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor _1. Mol Immunol, 33/11: 1799-1807 GM-0101
GM-0104
April 2006 Avadhanula V et al. (2006): Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol, 80/4: 1629-1636 GM-0501
March 2006 Nöckel J et al (2006): Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene. BMC Cancer, 6: 57 GM-0511
February 2006 Pavoni E et al. (2006): Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. BMC Cancer, 6: 41  
November 2005 Klaile E et al (2005): CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration. JCS, 118: 5513-5524 GM-0511
November 2005 Bade B et al (2005): Differential expression of the granzymes A, B, K, M and perforin in human peripheral blood lymphocytes. Int. Immunol, 17: 1419-1428  
October 2005 D'Amour K et al. (2005): Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol, 23: 1534-1541  
October 2005 Bratke K et al (2005): Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood. Eur J Immunol, 35/9: 2608-2616 GM-0202
October 2005 Bade B et al. (2005): Detection of soluble human granzyme K in vitro and in vivo. Eur J Immunol, 35/10:2940-2948 GM-0203
GM-0205
September 2005 Roessler et al (2005): Identification of Nicotinamide N-Methyltransferase as a novel serum tumor marker for colorectal cancer. Clin Cancer Res, 11/18: 6550-6558  
August 2005 Muenzner P et al (2005): CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol, 170/5: 825-836 GM-0505
May 2005 Neckermann S et al (2005): Presentation of the human Hepatitis B surface antigen–loop by the Cpn10 scaffold induces a specific antibody response in mice by genetic immunization. FOCiS annual meeting, Boston, Poster F2.39.  
April 2005 Kalina T et al (2005): Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens. BMC Cancer 5: 38 GM-0509
April 2005 Kunii R et al. (2005): Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13. J Periodontal Res, 40/2:138-46 GM-0101
December 2004 Nanda A et al. (2004): Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Res, 64: 8507-8511  
October 2004 Kammerer R et al. (2004): The tumour suppressor gene CEACAM1 is completely but reversibly downregulated in renal cell carcinoma. J Pathol, 204/3: 258-267. GM-0501
September 2004 Haynes C and BS Schnierle (2004): Retroviral vector targeting through insertion of epidermal growth factor into receptor binding deficient influenza A hemagglutinin results in fusion defective particles. J Virol Methods, 120/2: 189-199  
September 2004 Kiessling J et al. (2004): Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm. EMBO reports 5 /9: 889-894  
August 2004 Myrtek D et al. (2004): Expression of interleukin-13 receptor a 1-subunit on peripheral blood eosinophils is regulated by cytokines. Immunology, 112: 597-604  
May 2004 McCaw S et al. (2004): Engulfment of Neisseria gonorrhoeae: Revealing distinct processes of bacterial entry by individual carcinoembryonic antigen-related cellular adhesion molecule family receptors. Infection and Immunity, 72/5: 2742-2752 GM-0505
January 2004 Schmitter T et al. (2004): Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med, 199/1: 35-46. GM-0503
GM-0505
GM-0509
January 2004 Hakansson P et al (2004): Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a). Leukemia 18, 538–547 GM-0511
January 2004 Elagoz A et al. (2004): A truncated form of CKb8-1 is a potent agonist for human formyl peptide-receptor-like 1 receptor. Br J Pharmacol, 141/1: 37-46.  
January 2004 Bharti S (2004): Novel membrane protein shrew-1 targets to Cadherin-mediated junctions in polarized epithelial cells. Mol Biol Cell, 15: 397-406.  
December 2003 Fahlgren A et al. (2003): Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. Scand J Immunol, 58/6:628-641. GM-0508
November 2003 de Jonge MI et al. (2003): Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors. Mol Microbiol, 50/3: 1005  
October 2003 A shortcut from genomics to drug development. By Jens Lohrmann, Stefan Lang and John Thompson, published in Current Drug Discovery, October 2003. (For reprints please contact Dr. Stefan Lang.)  
May 2003 de Jonge MI et al. (2003): Functional activity of antibodies against the recombinant OpaJ protein from Neisseria meningitides. Infection and Immunity, 71/5:2331-2340  
February 2003 Custom-made antibodies produced by genetic immunisation: Applications in drug development, therapy and diagnosis. By Stefan Lang and John Thompson, published in Global Outsourcing Review, Vol. 5, No. 1, Spring 2003. (For reprints please contact Dr. Stefan Lang.)  
December 2002 Genetische Immunisierung zur Antikörperproduktion. Von Stefan Lang und John Thompson, veröffentlicht in transkript, 12/02, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.)  
October 2002 Bioprocessing - Genetic Immunization for Antibody Production. Tutorial: Genovac's Technological Shortcut From Gene to Antibody. By John Thompson, Ph.D., and Stefan Lang, Ph.D., published in Genetic Engineering News, Vol. 22, No. 17, October 1, 2002 (For reprints please contact Dr. Stefan Lang.)  
October 2002 Klippel S et al. (2002): Biochemical characterisation of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera. Blood, 100/7: 2441-2448  
September 2002 Genetische Immunisierung - ein hocheffizientes Verfahren zur Antikörper-Herstellung für die medizinische Diagnostik und Therapie. Von Stefan Lang und John Thompson, veröffentlicht in BIOspektrum, Sonderausgabe Proteomics & Drug Development, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.)  
August 2002 Bioprocessing - Capacity mismatch for production of monoclonals: Development-stage enhancements alleviate bottleneck. By Angelo DePalma, Ph.D., published in Genetic Engineering News, Vol. 22, No. 14, August 2002 (For reprints please contact Dr. Stefan Lang.)  
April 2002 Billker O et al. (2002): Distinct mechanisms of internalisation of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Pac1- and Cdc42-dependent and independent pathways. EMBO J, 21/4: 560-571 GM-0505
March 2002 Boulton IC and SD Gray-Owen (2002): Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes. Nat Immunol, 3/3:229-236 GM-0505
September 2001 Watt SM et al. (2001): Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site. Blood, 98/5: 1469-1479 GM-0504
GM-0505
GM-0511
September 2001 Richter G. et al. (2001): Tumor necrosis factor -alpha regulates the expression of ICOS ligand on CD34+ progenitor cells during differentiation into antigen presenting cells. J Biol Chem, 276/49: 45686-93 GM-0301
April 2000 Temerinac S et al. (2000): Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. Blood, 95/8: 2569-2576  
February 2000 Schoelzel S et al. (2000): Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol, 156/2: 595-605 GM-0505
GM-0508