| Date | Reference | Products |
|---|---|---|
| October 2016 | Königer et al (2016), ' Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA', Nature Microbiology | GM-0501 GM-0505 GM-0503 GM-0509 GM-0512 |
| July 2016 | Belvedere et al (2016), 'Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of formyl peptide receptor pathway', Scientific reports | GM-0601 |
| July 2016 | Simiele et al (2016), 'Epigenetic regulation of the formyl peptide receptor 2 gene', Biochemica et Biophyscia Acta | GM-0601 |
| May 2016 | Muenzner et al (2016), 'Uropathogenic E.coli exploit CEA to promote colonisation of the urogenital tract mucosa', PLos | GM-0501 GM-0505 GM-0509 |
| May 2016 | Liebler et al (2016), 'Towards a biofunctionalised vascular prosthesis: immune cell trapping via a growth factor receptor', J Tissue Eng Regen Med | GM-1006 GM-1007 |
| March 2016 | Fontana et al, 'Analysis of a spontaneous non-motile and avirulent mutant shows that FLiM is required for full endoflagella assembly in Leptospira interrogans' PLoS ONE | |
| March 2016 | Baumert et al, 'Hepatitis C virus cell entry: a target for novel antiviral strategies to address limitations of direct acting antivirals', Hepatol Int | |
| March 2016 | Schurmans et al, 'Specific expression and function of inositol 1,4,5-triphosphate 3-kinase C (ITPKC) in wild type and knock-out mice, Advances in Biological regulation (2016) 1-10 | |
| January 2016 | Schmohl et al (2016), Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk, Experimental Haematology | |
| August 2015 | (2015) 10th international Luebeck conference on the pathophysiology and pharmacology of erythropoietin and other hemopoietic growth factors. Am. J. Hematol., 90: E154–E180 | |
| July 2015 | Buettner et al, 9.O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. Nature Communications, 6:7673 | |
| July 2015 | Tchoupa et al (2015), Outer membrane protein P1 is the CEACAM-binding adhesin of Haemophilus Influenzae. Molecular Microbiology | |
| April 2015 | Tawar et al (2015), Claudins and pathogenesis of viral infection. Cell and Developmental Biology, 42:39-46 | |
| March 2015 | Mailly et al (2015), Clearance of persistent hepatitis C virus infection in humanised mice using claudin-1-targeting monoclonal antibody. Nature | GM-1110 GM-1111 |
| February 2015 | Linch et al (2015), OX40 agonists and combination immunotherapy: putting the pedal to the metal. Frontiers in Oncology 5, 34. | |
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| December 2014 | Belvedere et al (2014), 'Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells', BMC Cancer; 14:961 | GM-0601 |
| December 2014 | Dveksler et al (2014) Induction and activation of latent TGF-beta1 is carried out by two distinct domains of Pregnancy-specific Glycoprotein 1. The journal od biological chemistry | |
| December 2014 | Pierdomenico et al (2014) microRNA-181b regulates ALX/FPR2 expression and proresolution signaling in human macrophages. The journal of biological chemistry | GM-0601 |
| September 2014 | Isik et al (2014): Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL | |
| August 2014 | Filipovic et al. (2014) Anti-Nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. Breast cancer res treat. Aug 2014 | |
| June 2014 | Lombardo et al (2014): Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymeal transition in MCF7 breast cancer cells | |
| June 2014 | Denizot J et al (2014): Diet.Induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia Coli colonisation | GM-0509 |
| May 2014 | Goodrich A. et al (2014): Influence of a dual-injection regimen, plerixafor and CXCR4 on in utero hematopoietic stem cell transplantation and engraftment with use of the sheep model | GM-0805 |
| May 2014 | Xiao et al (2014): Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepititis C | |
| February 2014 | Zona et al (2014): CD81-Receptor associations - impact for hepatitis C virus entry and antiviral therapies | |
| January 2014 | Nadkarni S et al (2104): Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression. Circ Res. 114: 242-248, doi: 10.1161/CIRCRESAHA.114.301374 | GM-0601 |
| January 2014 | Peitsch C et al (2014): Activation of Influenza A Viruses by Host Proteases from Swine Airway Epithelium. J. Virol. 88/1: 282-291. 10.1128/JVI.01635-13 | |
| December 2013 | Curti et a (2013): OX40 is a potent immune-stimulating target in late-stage cancer patients, Cancer Res, 73:7189-7198 | |
| December 2013 | Neumann D et al (2013): Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation. Poster 2175 presented at the 55th ASH Meeting, New Orleans 7-10 Dec 2013. | GM-1202 |
| November 2013 | Hutchings CJ et al (2013): Monoclonal anti-β 1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment. mAbs 6/1, 10.4161/mabs.27226 | |
| November 2013 | He HQ et al (2103): Structural Determinants for the Interaction of Formyl Peptide Receptor 2 with Peptide Ligands. The Journal of Biological Chemistry, 289: 2295-2306. 10.1074/jbc.M113.509216 | GM-0601 |
| October 2013 | Liu et al (2013), 'Analysis of LGR4 receptor distribution in human and mouse tissues' PLOS One, 8:10 | |
| October 2013 | Patel PC et al (2013): Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties. J Biol Chem 288/41: 29654-69. 10.1074/jbc.M113.504639 | GM-0505 |
| October 2013 | Natoli A et al (2103): Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs. Int. J. Cancer, 133: 1945–1954. doi: 10.1002/ijc.28189 | GM-0104 |
| September 2013 | Rothmeier E et al (2013): Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection. PLoS Pathog 9(9): e1003598. doi:10.1371/journal.ppat.1003598 | |
| September 2013 | Fofana I et al (2013): Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies. J Virol.; 87(18): 10405-10. doi: 10.1128/JVI.01691-13 | GM-1110 GM-1111 GM-1112 |
| August 2013 | Klaile E et al (2013): Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons. Respiratory Res, 14:85 doi:10.1186/1465-9921-14-85 | |
| August 2013 | Denzau S et al (2013): Ontogenetic development of magnetic compass orientation in domestic chickens (Gallus gallus). J Exp Biol 216, 3143-3147.10.1242/jeb.088815 | |
| July 2013 | Johswich KO et al (2013): In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa. PLoS Pathog 9/7: e1003509. 10.1371/journal.ppat.1003509 | GM-0505 |
| July 2013 | Harbuzariu A et al (2013): CD34 affinity pheresis attenuates a surge among circulating progenitor cells following vascular injury. J Vascular Surgery, doi: 10.1016/j.jvs.2013.05.043 | GM-0805 |
| June 2013 | Miyahara T et al (2013): D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury. FASEB J. 27/6:2220-32. 10.1096/fj.12-225615. | GM-0601 |
| June 2013 | Meyer D et al (2013): Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. Biochem J. 452/2: 331-43. 10.1042/BJ20130101 | |
| June 2013 | Dalli J et al (2103): Proresolving and Tissue-Protective Actions of Annexin A1–Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor. The Journal of Immunology 190/12: 6478-6487. 10.4049/jimmunol.1203000 | GM-0601 |
| June 2013 | Bontjer I et al (2013): Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers. PLOS ONE 10.1371/journal.pone.0067484 | |
| May 2013 | Witzens-Harig M et al (2103): Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6. Blood 121/22: 4493-503. 10.1182/blood-2012-05-429415 | GM-0509 |
| May 2013 | Scheiter M et al (2013): Proteome analysis of distinct developmental stages of human natural killer (NK) cells. Mol Cell Proteomics 12/5: 1099-114. 10.1074/mcp.M112.024596 | GM-0908 |
| May 2013 | Fofana I et al (2013): A Novel Monoclonal Anti-CD81 Antibody Produced by Genetic Immunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission. PLoS ONE 8(5): e64221. doi:10.1371/journal.pone.0064221 | GM-1113 |
| May 2013 | Denzau S et al (2013): Different responses of two strains of chickens to different training procedures for magnetic directions. Animal cognition, 16/3: 395-403 | |
| March 2013 | Palin AC et al (2013): Human Neonatal Naive CD4+ T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a. J Immunol 190/6: 2682-2691, 10.4049/jimmunol.1202534 | |
| March 2013 | Meyer D et al (2013): Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. Biochem. J. 452/2: 331–343, 10.1042/BJ20130101 | |
| February 2013 | de Jong MF et al (2013): Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response. mBio 4/1, 10.1128/mBio.00418-12 | |
| January 2013 | Zhang et al (2013): Role of CEACAM1 and CEACAM20 in an In Vitro Model of Prostate Morphogenesis. PLOS ONE 10.1371/journal.pone.0053359 | |
| December 2012 | Zahid MN et al (2012): The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination. Hepatology. doi: 10.1002/hep.26097 | |
| December 2012 | Lotfi R et al (2102): Necrosis-Associated Factors (DAMPs) Including S100A4 Used to Pulse Dendritic Cells (DCs) Induce Regulatory T cells. J Cell Sci Ther 3:134. doi:10.4172/2157-7013.1000134 | |
| November 2012 | Kobayashi M et al (2012): Carcinoembryonic antigen-related cell adhesion molecules assurrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107/10: 1745-53. 10.1038/bjc.2012.422 | GM-0508 GM-0515 |
| November 2012 | Dakin SG et al (2102): Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. PLoS One 7/11: e48978. 10.1371/journal.pone.0048978 | GM-0601 |
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| September 2012 | Darrabie M et al (2012): Exposing cardiomyocytes to subclinical concentrations of doxorubicin rapidly reduces their creatine transport. American Journal of Physiology - Heart and Circulatory Physiology, 303/H539-H548, 10.1152/ajpheart.00108.2012 | |
| September 2012 | Bizzarro V et al (2012): Annexin A1 N-Terminal Derived Peptide Ac2-26 Stimulates Fibroblast Migration in High Glucose Conditions. PLoS ONE, 7(9), Sep 2012 | GM-0601 |
| August 2012 | Kemper et al (2012), 'Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells', Stem cells express | |
| August 2012 | Norling LV et al (2012): Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol.; 32(8): 1970-8. | GM-0601 |
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| May 2012 | Peng L et al (2012): The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA. PLoS One. 2012; 7(5): e36412. | GM-0503 |
| May 2012 | Partyka K et al (2012): Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification. J Proteome Res. 11/5: 2904-11. 10.1021/pr2012736 | GM-0503 |
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| April 2012 | Kammerer R et al (2012): Loss of the mammal-specific tectorial membrane component CEA cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies J. Biol. Chem., doi:10.1074/jbc.M111.320481 | GM-0518 |
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| March 2012 | Melchers M et al (2012): Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses. J Virol. 86(5):2488-500. doi: 10.1128/JVI.06259-1 | |
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| February 2012 | Haines DS et al (2012): Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking. Mol Cell Proteomics.10.1074/mcp.M111.016444 | GM-0804 |
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| December 2011 | Zhou J et al (2011): Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 23/9: 172. 10.1186/1477-7819-9-172 | GM-0508 |
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| August 2011 | de Lau W et al (2011): Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476/293, doi:10.1038/ nature10337 | |
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| May 2008 | Dalley D et al (2008): Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles). Tuberculosis 88/3: 235-243, doi:10.1016/j.tube.2007.11.001 | |
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| September 2006 | Maraqa L. et al (2006): CEACAM: A potential novel predictor of breast cancer recurrence. AACR Meeting Abstracts 2006 : PR-8 | GM-0506 |
| September 2006 | Technology Feature: 'Chain gang' delivers for hard labor. Nature Methods, 3/9: 753-762 | |
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| October 2003 | A shortcut from genomics to drug development. By Jens Lohrmann, Stefan Lang and John Thompson, published in Current Drug Discovery, October 2003. (For reprints please contact Dr. Stefan Lang.) | |
| May 2003 | de Jonge MI et al. (2003): Functional activity of antibodies against the recombinant OpaJ protein from Neisseria meningitides. Infection and Immunity, 71/5:2331-2340 | |
| February 2003 | Custom-made antibodies produced by genetic immunisation: Applications in drug development, therapy and diagnosis. By Stefan Lang and John Thompson, published in Global Outsourcing Review, Vol. 5, No. 1, Spring 2003. (For reprints please contact Dr. Stefan Lang.) | |
| December 2002 | Genetische Immunisierung zur Antikörperproduktion. Von Stefan Lang und John Thompson, veröffentlicht in transkript, 12/02, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.) | |
| October 2002 | Bioprocessing - Genetic Immunization for Antibody Production. Tutorial: Genovac's Technological Shortcut From Gene to Antibody. By John Thompson, Ph.D., and Stefan Lang, Ph.D., published in Genetic Engineering News, Vol. 22, No. 17, October 1, 2002 (For reprints please contact Dr. Stefan Lang.) | |
| October 2002 | Klippel S et al. (2002): Biochemical characterisation of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera. Blood, 100/7: 2441-2448 | |
| September 2002 | Genetische Immunisierung - ein hocheffizientes Verfahren zur Antikörper-Herstellung für die medizinische Diagnostik und Therapie. Von Stefan Lang und John Thompson, veröffentlicht in BIOspektrum, Sonderausgabe Proteomics & Drug Development, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.) | |
| August 2002 | Bioprocessing - Capacity mismatch for production of monoclonals: Development-stage enhancements alleviate bottleneck. By Angelo DePalma, Ph.D., published in Genetic Engineering News, Vol. 22, No. 14, August 2002 (For reprints please contact Dr. Stefan Lang.) | |
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| April 2000 | Temerinac S et al. (2000): Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. Blood, 95/8: 2569-2576 | |
| February 2000 | Schoelzel S et al. (2000): Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol, 156/2: 595-605 | GM-0505 GM-0508 |
