Date | Reference | Products |
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October 2016 | Königer et al (2016), ' Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA', Nature Microbiology | GM-0501 GM-0505 GM-0503 GM-0509 GM-0512 |
July 2016 | Belvedere et al (2016), 'Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of formyl peptide receptor pathway', Scientific reports | GM-0601 |
July 2016 | Simiele et al (2016), 'Epigenetic regulation of the formyl peptide receptor 2 gene', Biochemica et Biophyscia Acta | GM-0601 |
May 2016 | Muenzner et al (2016), 'Uropathogenic E.coli exploit CEA to promote colonisation of the urogenital tract mucosa', PLos | GM-0501 GM-0505 GM-0509 |
May 2016 | Liebler et al (2016), 'Towards a biofunctionalised vascular prosthesis: immune cell trapping via a growth factor receptor', J Tissue Eng Regen Med | GM-1006 GM-1007 |
March 2016 | Fontana et al, 'Analysis of a spontaneous non-motile and avirulent mutant shows that FLiM is required for full endoflagella assembly in Leptospira interrogans' PLoS ONE | |
March 2016 | Baumert et al, 'Hepatitis C virus cell entry: a target for novel antiviral strategies to address limitations of direct acting antivirals', Hepatol Int | |
March 2016 | Schurmans et al, 'Specific expression and function of inositol 1,4,5-triphosphate 3-kinase C (ITPKC) in wild type and knock-out mice, Advances in Biological regulation (2016) 1-10 | |
January 2016 | Schmohl et al (2016), Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk, Experimental Haematology | |
August 2015 | (2015) 10th international Luebeck conference on the pathophysiology and pharmacology of erythropoietin and other hemopoietic growth factors. Am. J. Hematol., 90: E154–E180 | |
July 2015 | Buettner et al, 9.O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. Nature Communications, 6:7673 | |
July 2015 | Tchoupa et al (2015), Outer membrane protein P1 is the CEACAM-binding adhesin of Haemophilus Influenzae. Molecular Microbiology | |
April 2015 | Tawar et al (2015), Claudins and pathogenesis of viral infection. Cell and Developmental Biology, 42:39-46 | |
March 2015 | Mailly et al (2015), Clearance of persistent hepatitis C virus infection in humanised mice using claudin-1-targeting monoclonal antibody. Nature | GM-1110 GM-1111 |
February 2015 | Linch et al (2015), OX40 agonists and combination immunotherapy: putting the pedal to the metal. Frontiers in Oncology 5, 34. | |
February 2015 | Maxwell P, et al. (2015). Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. Br. J. Haematol 168(3):429-42 | GM-1201 GM-1202 |
December 2014 | Belvedere et al (2014), 'Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells', BMC Cancer; 14:961 | GM-0601 |
December 2014 | Dveksler et al (2014) Induction and activation of latent TGF-beta1 is carried out by two distinct domains of Pregnancy-specific Glycoprotein 1. The journal od biological chemistry | |
December 2014 | Pierdomenico et al (2014) microRNA-181b regulates ALX/FPR2 expression and proresolution signaling in human macrophages. The journal of biological chemistry | GM-0601 |
September 2014 | Isik et al (2014): Enhanced immunogenicity of HIV-1 envelope gp140 proteins fused to APRIL | |
August 2014 | Filipovic et al. (2014) Anti-Nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. Breast cancer res treat. Aug 2014 | |
June 2014 | Lombardo et al (2014): Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymeal transition in MCF7 breast cancer cells | |
June 2014 | Denizot J et al (2014): Diet.Induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia Coli colonisation | GM-0509 |
May 2014 | Goodrich A. et al (2014): Influence of a dual-injection regimen, plerixafor and CXCR4 on in utero hematopoietic stem cell transplantation and engraftment with use of the sheep model | GM-0805 |
May 2014 | Xiao et al (2014): Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepititis C | |
February 2014 | Zona et al (2014): CD81-Receptor associations - impact for hepatitis C virus entry and antiviral therapies | |
January 2014 | Nadkarni S et al (2104): Investigational Analysis Reveals a Potential Role for Neutrophils in Giant-Cell Arteritis Disease Progression. Circ Res. 114: 242-248, doi: 10.1161/CIRCRESAHA.114.301374 | GM-0601 |
January 2014 | Peitsch C et al (2014): Activation of Influenza A Viruses by Host Proteases from Swine Airway Epithelium. J. Virol. 88/1: 282-291. 10.1128/JVI.01635-13 | |
December 2013 | Curti et a (2013): OX40 is a potent immune-stimulating target in late-stage cancer patients, Cancer Res, 73:7189-7198 | |
December 2013 | Neumann D et al (2013): Sensitive and Specific Antibody Probes Directed Against The Erythropoietin Receptor – From Basic Studies To Clinical Implementation. Poster 2175 presented at the 55th ASH Meeting, New Orleans 7-10 Dec 2013. | GM-1202 |
November 2013 | Hutchings CJ et al (2013): Monoclonal anti-β 1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment. mAbs 6/1, 10.4161/mabs.27226 | |
November 2013 | He HQ et al (2103): Structural Determinants for the Interaction of Formyl Peptide Receptor 2 with Peptide Ligands. The Journal of Biological Chemistry, 289: 2295-2306. 10.1074/jbc.M113.509216 | GM-0601 |
October 2013 | Liu et al (2013), 'Analysis of LGR4 receptor distribution in human and mouse tissues' PLOS One, 8:10 | |
October 2013 | Patel PC et al (2013): Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties. J Biol Chem 288/41: 29654-69. 10.1074/jbc.M113.504639 | GM-0505 |
October 2013 | Natoli A et al (2103): Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs. Int. J. Cancer, 133: 1945–1954. doi: 10.1002/ijc.28189 | GM-0104 |
September 2013 | Rothmeier E et al (2013): Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection. PLoS Pathog 9(9): e1003598. doi:10.1371/journal.ppat.1003598 | |
September 2013 | Fofana I et al (2013): Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies. J Virol.; 87(18): 10405-10. doi: 10.1128/JVI.01691-13 | GM-1110 GM-1111 GM-1112 |
August 2013 | Klaile E et al (2013): Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons. Respiratory Res, 14:85 doi:10.1186/1465-9921-14-85 | |
August 2013 | Denzau S et al (2013): Ontogenetic development of magnetic compass orientation in domestic chickens (Gallus gallus). J Exp Biol 216, 3143-3147.10.1242/jeb.088815 | |
July 2013 | Johswich KO et al (2013): In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa. PLoS Pathog 9/7: e1003509. 10.1371/journal.ppat.1003509 | GM-0505 |
July 2013 | Harbuzariu A et al (2013): CD34 affinity pheresis attenuates a surge among circulating progenitor cells following vascular injury. J Vascular Surgery, doi: 10.1016/j.jvs.2013.05.043 | GM-0805 |
June 2013 | Miyahara T et al (2013): D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury. FASEB J. 27/6:2220-32. 10.1096/fj.12-225615. | GM-0601 |
June 2013 | Meyer D et al (2013): Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. Biochem J. 452/2: 331-43. 10.1042/BJ20130101 | |
June 2013 | Dalli J et al (2103): Proresolving and Tissue-Protective Actions of Annexin A1–Based Cleavage-Resistant Peptides Are Mediated by Formyl Peptide Receptor 2/Lipoxin A4 Receptor. The Journal of Immunology 190/12: 6478-6487. 10.4049/jimmunol.1203000 | GM-0601 |
June 2013 | Bontjer I et al (2013): Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers. PLOS ONE 10.1371/journal.pone.0067484 | |
May 2013 | Witzens-Harig M et al (2103): Tumor cells in multiple myeloma patients inhibit myeloma-reactive T cells through carcinoembryonic antigen-related cell adhesion molecule-6. Blood 121/22: 4493-503. 10.1182/blood-2012-05-429415 | GM-0509 |
May 2013 | Scheiter M et al (2013): Proteome analysis of distinct developmental stages of human natural killer (NK) cells. Mol Cell Proteomics 12/5: 1099-114. 10.1074/mcp.M112.024596 | GM-0908 |
May 2013 | Fofana I et al (2013): A Novel Monoclonal Anti-CD81 Antibody Produced by Genetic Immunization Efficiently Inhibits Hepatitis C Virus Cell-Cell Transmission. PLoS ONE 8(5): e64221. doi:10.1371/journal.pone.0064221 | GM-1113 |
May 2013 | Denzau S et al (2013): Different responses of two strains of chickens to different training procedures for magnetic directions. Animal cognition, 16/3: 395-403 | |
March 2013 | Palin AC et al (2013): Human Neonatal Naive CD4+ T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a. J Immunol 190/6: 2682-2691, 10.4049/jimmunol.1202534 | |
March 2013 | Meyer D et al (2013): Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. Biochem. J. 452/2: 331–343, 10.1042/BJ20130101 | |
February 2013 | de Jong MF et al (2013): Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response. mBio 4/1, 10.1128/mBio.00418-12 | |
January 2013 | Zhang et al (2013): Role of CEACAM1 and CEACAM20 in an In Vitro Model of Prostate Morphogenesis. PLOS ONE 10.1371/journal.pone.0053359 | |
December 2012 | Zahid MN et al (2012): The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination. Hepatology. doi: 10.1002/hep.26097 | |
December 2012 | Lotfi R et al (2102): Necrosis-Associated Factors (DAMPs) Including S100A4 Used to Pulse Dendritic Cells (DCs) Induce Regulatory T cells. J Cell Sci Ther 3:134. doi:10.4172/2157-7013.1000134 | |
November 2012 | Kobayashi M et al (2012): Carcinoembryonic antigen-related cell adhesion molecules assurrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107/10: 1745-53. 10.1038/bjc.2012.422 | GM-0508 GM-0515 |
November 2012 | Dakin SG et al (2102): Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. PLoS One 7/11: e48978. 10.1371/journal.pone.0048978 | GM-0601 |
October 2012 | Lotfi R et al (2012): Nekrose-assoziierte Faktoren (DAMPs) beschleunigen nicht nur die Tumorproliferation sondern beeinflussen auch die adaptive Immunantwort. Bedeutung von S100A4 im Tumormilieu. Abstract of the annual meeting of the DGHO, Stuttgart 19.-23.10.2012 | GM-0908 |
September 2012 | Darrabie M et al (2012): Exposing cardiomyocytes to subclinical concentrations of doxorubicin rapidly reduces their creatine transport. American Journal of Physiology - Heart and Circulatory Physiology, 303/H539-H548, 10.1152/ajpheart.00108.2012 | |
September 2012 | Bizzarro V et al (2012): Annexin A1 N-Terminal Derived Peptide Ac2-26 Stimulates Fibroblast Migration in High Glucose Conditions. PLoS ONE, 7(9), Sep 2012 | GM-0601 |
August 2012 | Kemper et al (2012), 'Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells', Stem cells express | |
August 2012 | Norling LV et al (2012): Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol.; 32(8): 1970-8. | GM-0601 |
July 2012 | Bena S et al (2012): Annexin A1 Interaction with the FPR2/ALX Receptor. Identification of distinct domains and downstream associated signaling. J Biol Chem, 287(29): 24690–24697. | GM-0601 |
June 2012 | Voges M et al (2012): Extracellular IgC2 Constant Domains of CEACAMs Mediate PI3K Sensitivity during Uptake of Pathogens. PLoS One. 2012; 7(6): e39908. | GM-0505 |
June 2012 | Klarenbeck A et al (2012): Targeting chemokines and chemokine receptors with antibodies. Drug Discovery Today: Technologies, http://dx.doi.org/10.1016/j.ddtec.2012.05.003 | |
May 2012 | Peng L et al (2012): The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA. PLoS One. 2012; 7(5): e36412. | GM-0503 |
May 2012 | Partyka K et al (2012): Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification. J Proteome Res. 11/5: 2904-11. 10.1021/pr2012736 | GM-0503 |
May 2012 | Drukker M et al (2012): Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol. 30/6: 531-42. 10.1038/nbt.2239 | GM-0503 |
April 2012 | Kammerer R et al (2012): Loss of the mammal-specific tectorial membrane component CEA cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies J. Biol. Chem., doi:10.1074/jbc.M111.320481 | GM-0518 |
April 2012 | Fagerhol MK et al (2102): Large molecular size EDTA-resistant complexes containing S100A12, ERAC, in serum during inflammatory conditions. Scandinavian Journal of Clinical & Laboratory Investigation 72/2: 129-136, 10.3109/00365513.2011.643819 | |
March 2012 | Talekar A (2012): Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment. PLoS One. 2012; 7(3): e30538. | |
March 2012 | Melchers M et al (2012): Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses. J Virol. 86(5):2488-500. doi: 10.1128/JVI.06259-1 | |
March 2012 | Christianson GJ et al (2012): Monoclonal antibodies directed against human FcRn and their applications. MAbs Mar 1;4(2). PMID 22453095 | GM-0808 GM-0809 |
February 2012 | Haines DS et al (2012): Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking. Mol Cell Proteomics.10.1074/mcp.M111.016444 | GM-0804 |
February 2012 | Dalli J et al (2012): Annexin A1 N-Terminal Derived Peptide Ac2-26 Exerts Chemokinetic Effects on Human Neutrophils. Frontiers in Pharmacology, 3: 28, doi:10.3389/fphar.2012.00028 | GM-0601 |
February 2012 | Dakin SG et al (2102): Macrophage sub-populations and the lipoxin A4 receptor implicate active inflammation during equine tendon repair.PLoS One 7/2: e32333. 10.1371/journal.pone.0032333 | GM-0601 |
January 2012 | Sarantis H and SD Gray-Owen (2012): Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae. Infect Immun. 80/1: 345-58. 10.1128/IAI.05702-11 | GM-0505 GM-0509 GM-0511 GM-0512 |
January 2012 | Pesce L et al (2012): TSH Regulates Pendrin Membrane Abundance and Enhances Iodide Efflux in Thyroid Cells. Endocrinology, 153(1): 512–521. 10.1210/en.2011-1548 | |
December 2011 | Zhou J et al (2011): Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 23/9: 172. 10.1186/1477-7819-9-172 | GM-0508 |
November 2011 | Simiele F et al (2011): Transcriptional regulation of the human FPR2/ALX gene: evidence of a heritable genetic variant that impairs promoter activity. FASEB 11-198069. | GM-0601 |
November 2011 | Burden CS et al (2011): A monolith purification process for virus-like particles from yeast homogenate. Journal of Chromatography B, doi:10.1016/j.jchromb.2011.10.044 | |
November 2011 | Hermann RJ et al (2011): Characterization and use of a rabbit-anti-mouse VPAC1 antibody by flow cytometry. Journal of Immunological Methods, doi:10.1016/j.jim.2011.10.009 | |
October 2011 | Balenga NAB et al (2011): GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. Cell Res. 21(10): 1452–1469 | |
October 2011 | Weinberg A et al (2011): Science gone translational: the OX40 agonist story. Immunological Reviews 244/1: 218-231 | |
August 2011 | de Lau W et al (2011): Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476/293, doi:10.1038/ nature10337 | |
July 2011 | Queval CJ et al (2011): Role of Src Kinases in Mobilization of Glycosylphosphatidylinositol-Anchored Decay-Accelerating Factor by Dr Fimbria-Positive Adhering Bacteria. Infect. Immun. 79/7: 2519-2534. 10.1128/IAI.01052-1 | GM-0505 |
July 2011 | Graham SA et al (2011): Identification of neutrophil granule glycoproteins as Lewis(x)-containing ligands cleared by the scavenger receptor C-type lectin. J Biol Chem 286/27: 24336-49. 10.1074/jbc.M111.244772 | GM-0504 |
June 2011 | van Montfort T et al (2011): A Chimeric HIV-1 Envelope Glycoprotein Trimer with an Embedded Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Domain Induces Enhanced Antibody and T Cell Responses. JBC, 286, 22250-22261 | |
June 2011 | Moreland AJ et al (2011): Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques. BMC Genomics 12/295. 10.1186/1471-2164-12-295 | GM-0504 |
June 2011 | Green LR et al (2011): Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells. Infect Immun 79/6:2241-9. 10.1128/IAI.01354-10 | GM-0505 |
June 2011 | Denizot J et al (2012): Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients. Inflamm Bowel Dis, 18: 294–304. 10.1002/ibd.21787 | GM-0509 |
May 2011 | Niessner C et al (2011): Avian Ultraviolet/Violet Cones Identified as Probable Magnetoreceptors. PLoS One. 2011; 6(5): e20091. | |
May 2011 | Liévin-Le Moal V et al (2011): Apical expression of human full-length hCEACAM1-4L protein renders the Madin Darby Canine Kidney cells responsive to lipopolysaccharide leading to TLR4-dependent Erk1/2 and p38 MAPK signalling. Cellular Microbiology, 13: 764–785. 10.1111/j.1462-5822.2011.01575.x | GM-0505 |
May 2011 | Vomhof-DeKrey EE et al (2011):Vasoactive intestinal peptide receptor 1 is downregulated during expansion of antigen-specific CD8 T cells following primary and secondary Listeria monocytogenes infections. J Neuroimmunol, 234/1–2: 40–48, 10.1016/j.jneuroim.2011.02.002 | |
April 2011 | Deuquet J et al (2011): Hyaline Fibromatosis Syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors. EMBO Mol Med. 2011 April; 3(4): 208–221. 10.1002/emmm.201100124 | |
April 2011 | Brancaleone V et al (2011): Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature. JImmunol 186/8, 4905-4914 | GM-0601 |
April 2011 | Zaremba A, Schmuecker U and Esche H (2011): Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway.Virology Journal 2011, 8:192 | |
March 2011 | Seizer P et al (2011): Disrupting the Extracellular Matrix Metalloproteinase Inducer–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion. ATVBAHA, 10.1161/ATVBAHA.111.225771 | |
March 2011 | Seizer P et al (2011): Disrupting the EMMPRIN (CD147)–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion. Arteriosclerosis, Thrombosis, and Vascular Biology, 31: 1377-1386. 10.1161/ATVBAHA.111.225771 | |
March 2011 | Porotto M et al (2011): Synthetic protocells interact with viral nanomachinery and inactivate pathogenic human virus. PLoS One. 2011; 6(3): e16874. | |
January 2011 | Kuespert K et al (2011): Neisseria meningitidis has two independent modes of recognizing its human receptor CEACAM1. PLoS One. 2011; 6(1): e14609. | GM-0505 GM-0511 |
December 2010 | Hutchings CJ et al (2010): Therapeutic antibodies directed at G protein-coupled receptors. mAbs 2/6, 594-606. | |
December 2010 | Legrand F et al (2010): Human Eosinophils Exert TNF-α and Granzyme A-Mediated Tumoricidal Activity toward Colon Carcinoma Cells. JImmunol 185/12, 7443-7451 | |
November 2010 | Zeisel M et al (2010): Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. J Hepatol, doi:10.1016/j.jhep.2010.10.014 | |
November 2010 | De Santo C et al (2010): Invariant NKT cells modulate the suppressive activity of Serum Amyloid A-differentiated IL-10-secreting neutrophils. Nat Immunol.; 11(11): 1039–1046. | GM-0601 |
October 2010 | Spurr L et al (2010): Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets. International Immunopharmacology, doi:10.1016/j.intimp.2010.10.006 | GM-0601 |
October 2010 | Rolhion N et al (2010): Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion. Gut, 59/10: 1355-6 | GM-0509 |
October 2010 | Weibel R et al (2010): Development of Standard Test Procedures for Quantifying Carry Over from Fixed Pipetting Tips in Liquid-Handling Systems. J Ass Lab Auto, 15/5: 369-378 | |
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September 2010 | Xianfeng Chen, Angela Shaulov Kask, et al (2010) Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays, Journal of Controlled Release, Volume 148, Issue 3, 20 December 2010, Pages 327-333, ISSN 0168-3659, DOI: 10.1016/j.jconrel.2010.09.001. | |
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April 2010 | Betts AM et al (2010): The Application of Target Information and Preclinical Pharmacokinetic/Pharmacodynamic Modeling in Predicting Clinical Doses of a Dickkopf-1 Antibody for Osteoporosis. JPet, 333/1, 2-13 | |
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August 2009 | Gross JC et al (2009): E-cadherin Surface Levels in Epithelial Growth Factor-stimulated Cells Depend on Adherens Junction Protein Shrew-1. MBoC 20/15: 3598-3607 | |
July 2009 | Yue T et al (2009): The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. Mol Cell Proteomics. 8(7): 1697-707. | GM-0501 GM-0505 GM-0508 GM-0509 |
July 2009 | Bratke et al (2009): Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4+ T cells by down-regulation of granzyme B. Immunology. 127/3: 338–344 | GM-0202 |
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May 2009 | Martins V et al (2009): ATLa, an Aspirin-Triggered Lipoxin A4 Synthetic Analog, Prevents the Inflammatory and Fibrotic Effects of Bleomycin-Induced Pulmonary Fibrosis. J Immunol, 182: 5374 -5381 | GM-0601 |
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February 2009 | Semiramoth N et al (2009): Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase -and MAPK- dependent mechanism. J Leukocyte Biol, 85, 1-12 | GM-0501 GM-0509 |
January 2009 | Guignot J et al. (2009): Human decay-accelerating factor and CEACAM receptor-mediated internalization and intracellular lifestyle of Afa/Dr diffusely adhering escherichia coli in epithelial cells. Infection and Immunity, 77/1, 517-531 | GM-0505 |
December 2008 | Polymenidou M et al. (2008): The POM Monoclonals: A comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS ONE ; 3/12: e3872. | |
December 2008 | Porada CD et al (2008): Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells. Exp Hematol, 36/12: 1739-1749 | GM-0805 |
November 2008 | Hooper JW, et al (2008): Immune serum produced by DNA vaccination protects hamsters against lethal respiratory challenge with Andes virus. FJ Virol., 82(3):1332-8. | |
November 2008 | Beaslas O et al (2008): Transcriptome response of enterocytes to dietary lipids: impact on cell architecture, signaling, and metabolism genes. Am J Physiol Gastrointest Liver Physiol, 295/5: G942-52 | GM-0501 |
July 2008 | Paulmann D et al. (2008): Hepatitis A virus protein 2B suppresses beta interferon (IFN) gene transcription by interfering with IFN regulatory factor 3 activation. J Gen Virol 89, 1593-1604 | |
June 2008 | Thomas SN et al. (2008): Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow. J Biol Chem, 283: 15647-55. | GM-0501 GM-0507 GM-0508 GM-0509 |
June 2008 | Planaguama A et al (2008): Airway Lipoxin A4 Generation and Lipoxin A4 Receptor Expression Are Decreased in Severe Asthma. Am J Respir Crit Care Med, 178a: 574-582 | GM-0601 |
June 2008 | Nittka S et al (2008): The CEACAM1-mediated apoptosis pathway is activated by CEA and triggers dual cleavage of CEACAM1 Activation and processing of CEACAM1 during apoptosis. Oncogene 27, 3721-3728 | GM-0501 |
May 2008 | Lee HSW et al (2008): CEACAM1 Dynamics during Neisseria gonorrhoeae Suppression of CD4+ T Lymphocyte Activation. J Immunol, 180: 6827-6835 | GM-0505 |
May 2008 | Dalley D et al (2008): Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles). Tuberculosis 88/3: 235-243, doi:10.1016/j.tube.2007.11.001 | |
February 2008 | Björkman L et al (2008): Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1. J Leukoc Biol, 83: 245-53 | GM-0601 |
December 2007 | Yoon J et al (2007): CD66b regulates adhesion and activation of human eosinophils. J Immunol, 179: 8454-62 | GM-0501 GM-0512 |
December 2007 | Zeisel M et al. (2007): Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology, 46/6:1722-31 | |
December 2007 | Riesenberg R et al (2007): Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma. Clin Cancer Res, 13/23, 6993-7002 | GM-0511 |
December 2007 | Kilic N et al (2007): Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1. Blood, 110/13, 4223-4233 | GM-0508 GM-0509 GM-0511 |
August 2007 | Schmitter T et al (2007): Opa proteins of pathogenic neisseriae initiate Src kinase-dependent or lipid raft-mediated uptake via distinct human carcinoembryonic antigen-related cell adhesion molecule isoforms. Infect Immun, 75/8:4116-26. | GM-0505 |
June 2007 | Bonn S et al (2007): Combinatorial expression of α- and γ-protocadherins alters their presenilin-dependent processing. Mol Cell Biol, 27/11: 4121-4132 | |
May 2007 | Morris NP et al (2007): Development and characterization of recombinant human Fc:OX40L fusion protein linked via a coiled-coil trimerization domain. Mol Immunol 44/12: 3112-3121 | |
May 2007 | Catanese MT et al. (2007): High avidity monoclonal antibodies against human scavenger receptor class B type I efficiently block hepatitis C virus infection in the presence of HDL. J Virol, 2007 0: JVI.00193-07 | |
April 2007 | Schreiner A et al. (2007): Junction protein Shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147. Mol Biol Cell, 18/4:1272-81 | |
March 2007 | Vicovac L et al (2007):Carcinoembryonic Antigen and Related Molecules in Normal and Transformed Trophoblast. Placenta 28/2-3:85-96, doi:10.1016/j.placenta.2006.02.002 | |
February 2007 | Chan CHF et al. (2007): Colorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice. PLoS ONE, 2/12: e1353 | GM-0509 |
January 2007 | Viswanathan A et al. (2007): Functional expression of N-formyl peptide receptors in human bone marrow-derived mesenchymal stem cells. Stem Cells, 25/5:1263-9 | GM-0601 |
December 2006 | Weinberg AD et al. (2006): Anti-OX40 (CD134) Administration to nonhuman primates: immunostimulatory effects and toxicokinetic study. J Immunother, 29/6: 575-585 | |
November 2006 | Ellies D et al. (2006): Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res, 21/11:1738-49 | |
October 2006 | D'Amour K et al (2006): Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol, 24/1: 1392-1401 | |
September 2006 | Maraqa L. et al (2006): CEACAM: A potential novel predictor of breast cancer recurrence. AACR Meeting Abstracts 2006 : PR-8 | GM-0506 |
September 2006 | Technology Feature: 'Chain gang' delivers for hard labor. Nature Methods, 3/9: 753-762 | |
May 2006 | Tsutsumida H et al (2006): RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells. Clin Cancer Res, 12: 2976-87 | GM-0506 |
April 2006 | Krause S et al. (2006): Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor _1. Mol Immunol, 33/11: 1799-1807 | GM-0101 GM-0104 |
April 2006 | Avadhanula V et al. (2006): Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol, 80/4: 1629-1636 | GM-0501 |
March 2006 | Nöckel J et al (2006): Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene. BMC Cancer, 6: 57 | GM-0511 |
February 2006 | Pavoni E et al. (2006): Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. BMC Cancer, 6: 41 | |
November 2005 | Klaile E et al (2005): CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration. JCS, 118: 5513-5524 | GM-0511 |
November 2005 | Bade B et al (2005): Differential expression of the granzymes A, B, K, M and perforin in human peripheral blood lymphocytes. Int. Immunol, 17: 1419-1428 | |
October 2005 | D'Amour K et al. (2005): Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol, 23: 1534-1541 | |
October 2005 | Bratke K et al (2005): Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood. Eur J Immunol, 35/9: 2608-2616 | GM-0202 |
October 2005 | Bade B et al. (2005): Detection of soluble human granzyme K in vitro and in vivo. Eur J Immunol, 35/10:2940-2948 | GM-0203 GM-0205 |
September 2005 | Roessler et al (2005): Identification of Nicotinamide N-Methyltransferase as a novel serum tumor marker for colorectal cancer. Clin Cancer Res, 11/18: 6550-6558 | |
August 2005 | Muenzner P et al (2005): CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol, 170/5: 825-836 | GM-0505 |
May 2005 | Neckermann S et al (2005): Presentation of the human Hepatitis B surface antigen–loop by the Cpn10 scaffold induces a specific antibody response in mice by genetic immunization. FOCiS annual meeting, Boston, Poster F2.39. | |
April 2005 | Kalina T et al (2005): Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens. BMC Cancer 5: 38 | GM-0509 |
April 2005 | Kunii R et al. (2005): Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13. J Periodontal Res, 40/2:138-46 | GM-0101 |
December 2004 | Nanda A et al. (2004): Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Res, 64: 8507-8511 | |
October 2004 | Kammerer R et al. (2004): The tumour suppressor gene CEACAM1 is completely but reversibly downregulated in renal cell carcinoma. J Pathol, 204/3: 258-267. | GM-0501 |
September 2004 | Haynes C and BS Schnierle (2004): Retroviral vector targeting through insertion of epidermal growth factor into receptor binding deficient influenza A hemagglutinin results in fusion defective particles. J Virol Methods, 120/2: 189-199 | |
September 2004 | Kiessling J et al. (2004): Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm. EMBO reports 5 /9: 889-894 | |
August 2004 | Myrtek D et al. (2004): Expression of interleukin-13 receptor a 1-subunit on peripheral blood eosinophils is regulated by cytokines. Immunology, 112: 597-604 | |
May 2004 | McCaw S et al. (2004): Engulfment of Neisseria gonorrhoeae: Revealing distinct processes of bacterial entry by individual carcinoembryonic antigen-related cellular adhesion molecule family receptors. Infection and Immunity, 72/5: 2742-2752 | GM-0505 |
January 2004 | Schmitter T et al. (2004): Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med, 199/1: 35-46. | GM-0503 GM-0505 GM-0509 |
January 2004 | Hakansson P et al (2004): Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a). Leukemia 18, 538–547 | GM-0511 |
January 2004 | Elagoz A et al. (2004): A truncated form of CKb8-1 is a potent agonist for human formyl peptide-receptor-like 1 receptor. Br J Pharmacol, 141/1: 37-46. | |
January 2004 | Bharti S (2004): Novel membrane protein shrew-1 targets to Cadherin-mediated junctions in polarized epithelial cells. Mol Biol Cell, 15: 397-406. | |
December 2003 | Fahlgren A et al. (2003): Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. Scand J Immunol, 58/6:628-641. | GM-0508 |
November 2003 | de Jonge MI et al. (2003): Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors. Mol Microbiol, 50/3: 1005 | |
October 2003 | A shortcut from genomics to drug development. By Jens Lohrmann, Stefan Lang and John Thompson, published in Current Drug Discovery, October 2003. (For reprints please contact Dr. Stefan Lang.) | |
May 2003 | de Jonge MI et al. (2003): Functional activity of antibodies against the recombinant OpaJ protein from Neisseria meningitides. Infection and Immunity, 71/5:2331-2340 | |
February 2003 | Custom-made antibodies produced by genetic immunisation: Applications in drug development, therapy and diagnosis. By Stefan Lang and John Thompson, published in Global Outsourcing Review, Vol. 5, No. 1, Spring 2003. (For reprints please contact Dr. Stefan Lang.) | |
December 2002 | Genetische Immunisierung zur Antikörperproduktion. Von Stefan Lang und John Thompson, veröffentlicht in transkript, 12/02, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.) | |
October 2002 | Bioprocessing - Genetic Immunization for Antibody Production. Tutorial: Genovac's Technological Shortcut From Gene to Antibody. By John Thompson, Ph.D., and Stefan Lang, Ph.D., published in Genetic Engineering News, Vol. 22, No. 17, October 1, 2002 (For reprints please contact Dr. Stefan Lang.) | |
October 2002 | Klippel S et al. (2002): Biochemical characterisation of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera. Blood, 100/7: 2441-2448 | |
September 2002 | Genetische Immunisierung - ein hocheffizientes Verfahren zur Antikörper-Herstellung für die medizinische Diagnostik und Therapie. Von Stefan Lang und John Thompson, veröffentlicht in BIOspektrum, Sonderausgabe Proteomics & Drug Development, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.) | |
August 2002 | Bioprocessing - Capacity mismatch for production of monoclonals: Development-stage enhancements alleviate bottleneck. By Angelo DePalma, Ph.D., published in Genetic Engineering News, Vol. 22, No. 14, August 2002 (For reprints please contact Dr. Stefan Lang.) | |
April 2002 | Billker O et al. (2002): Distinct mechanisms of internalisation of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Pac1- and Cdc42-dependent and independent pathways. EMBO J, 21/4: 560-571 | GM-0505 |
March 2002 | Boulton IC and SD Gray-Owen (2002): Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes. Nat Immunol, 3/3:229-236 | GM-0505 |
September 2001 | Watt SM et al. (2001): Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site. Blood, 98/5: 1469-1479 | GM-0504 GM-0505 GM-0511 |
September 2001 | Richter G. et al. (2001): Tumor necrosis factor -alpha regulates the expression of ICOS ligand on CD34+ progenitor cells during differentiation into antigen presenting cells. J Biol Chem, 276/49: 45686-93 | GM-0301 |
April 2000 | Temerinac S et al. (2000): Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. Blood, 95/8: 2569-2576 | |
February 2000 | Schoelzel S et al. (2000): Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol, 156/2: 595-605 | GM-0505 GM-0508 |