In Stock, Royalty-Free, Packaging Plasmid Solution for Recombinant AAV Manufacturing
pALD-AAV Rep/Cap Plasmids
Recombinant AAV (rAAV) manufacturing is composed of four main parts which include a rep/cap plasmid, a helper plasmid, an expression plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method.
Aldevron's pALD-AAV rep/cap plasmids have several advantages:
- Royalty free, including for commercial products
- Kanamycin resistance
- Consistent, reliable supply
- Immediately available at research grade
With Aldevron's rep/cap plasmids, clients do not need to manufacture a custom batch as Aldevron maintains each as an in-stock product, reducing timeline and cost.
Each rep/cap plasmid contains the gene sequence for AAV serotype 2 replication (rep) protein paired with either serotype 2, 5 or 6 capsid (cap) protein respectively. Use of AAV serotype 2 rep proteins in combination with other serotypes for cap proteins is referred to as pseudotyping which provides enhanced and refined tissue tropism in some applications.
Plasmid | Rep Serotype | Cap Serotype | Pack Size |
pALD-AAV2 | 2 | 2 | 10 mg |
pALD-AAV5 | 2 | 5 | 10 mg |
pALD-AAV6 | 2 | 6 | 10 mg |
Bulk quantities and samples are available upon request.
Plasmid Maps
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*Sequence files require SnapGene Viewer or other program for viewing sequence data
Description | Cat # | Price | Order |
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pALD-AAV2 |
5057-10 |
5057-10 10 mg Pricing
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pALD-AAV5 |
5058-10 |
5058-10 10 mg Pricing
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pALD-AAV6 |
5059-10 |
5059-10 10 mg Pricing
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