Reliable antibody sequencing is critical to lead discovery and the development of therapeutic antibodies. GENOVAC understands that knowledge of the variable regions is an obligatory entry point for humanization.
Filling that requirement, GENOVAC’s antibody sequencing services are designed to prevent amplification of aberrant light chains and other undesirable intermediates of the immunoglobulin gene maturation process. We provide:
- Variable region sequencing
- Variable-plus leader region sequencing
- Full-length heavy and light chain sequencing
Our sequencing projects begin with flash-frozen or RNA-stabilized hybridoma cells, concluding with a detailed project report that includes subsequent trace files and complete, annotated sequences of the relevant regions.