Aldevron Breakthrough Blog: conferences

LNPs, analytics and mRNA

Working toward advanced analytical techniques

Guten tag from Berlin! As an analytically minded-person, it’s fascinating to connect with colleagues from around the world to discuss cutting-edge techniques and strategies for ensuring the quality, efficacy, and safety of mRNA-based therapeutics. That fascination led me to the mRNA Analytical Development Summit, held in Germany's capital city.

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Climbing Towards the mRNA Summit

Celebrating the work ahead

On my flight to Boston for the mRNA-Based Therapeutics Summit, I followed my usual routine as an uneasy flier; put headphones on and tune out until landing. This time, however, the music continued as I found certain lyrics of one particular song repeating in my mind throughout the two-day gathering of industry leaders:
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Cures and Inspirations

ASGCT highlights transformational approaches

When it comes to large events, the best place to be is front and center. And at the 26th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT) in Los Angeles, that’s where we were, right inside the door in the middle of the exhibition hall. Not only were we able to greet nearly everyone who came to the exhibits, for the first time we joined other Danaher companies in one centralized location, allowing us to jointly highlight the Danaher mission, helping people realize life’s potential, to clients, partners and the industry in general.

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An evolution at TIDES

mRNA joins the mix

In the past, the TIDES USA conference event has been focused on oligonucleotide and peptide therapeutics, providing information on development trends and technologies for those industry segments. That is changing now, with an additional focus on mRNA therapeutics coming into the mix. 

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Advancing through Disruption

Achieving advancement in ATMP regulation through disruptive innovation of European healthcare systems

Partnerships and transformation are a large part of our evolving biotech landscape. Not surprisingly, they were two common themes at this year’s Meeting on the Med in Barcelona.  As an example, attendees discussed how the lack of harmonization across EU member states has led to fragmented access to advanced therapy medicinal products (ATMPs), which varies from country to country. Chris Fox, president of Novartis Gene Therapies, used her company’s product, ZOLGENSMA®, as an example. It’s approved for use in 48 countries but is only accessible in 35. 

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Quick T-Cell Education

A new means to fight stem cell transplant infections

When attending a large event such as Advanced Therapies Week, you are able to reach outside your regular workspace and learn about numerous developments happening in other spaces. One in particular that I learned of is an exciting advance in a new ex vivo cell therapy from Smart Immune. It's designed to help those who receive allogenic bone marrow transplants as part of treatment for cancer, such as leukemia, lymphoma, or myeloma, which can leave a patient in an immunosuppressive state.
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Expanding an Analytical Framework

Increased expectations, increased accountability

Rapid evolution. In short, that’s what we’re seeing in the method development and assay life cycle field. The concepts have been around for quite some time, but now with updated and new guidance for analytical life cycle and analytical method development, we’re seeing a more dynamic period emerging in the space. This includes increased expectations for analytical method development and increased accountability for reporting development data.

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Looking back at 2022

Four events that made it a great year

I must admit, I’m a sucker for just about any list article. Show me a title such as, “8 Reasons Why…” or “10 Movies That…”, and there’s a pretty good chance I’ll click. I often find myself scrolling through the strangest lists, reviewing things that I really don’t care about – kitchen gadgets, closet organizing products, stocking stuffers. I’m hopeless. I’m compelled to click.

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Fast Advances Highlight CRISPR 2.0

A focus on personalized therapeutics

Genomic medicine field has progressed in leaps and bounds these last few years, and at the 3rd Annual CRISPR 2.0 conference, it was wonderful to again connect in person with colleagues to discuss those advances. It was a great opportunity to listen and learn from a prestigious lineup of gene editing experts from across the industry.

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Aiming for improved delivery, safety, at ESGCT

Covering multiple modalities

Every year, October marks the change in the season, the dropping of temperatures, and the height of conference season for biotech. This year’s ESGCT meeting in Edinburgh, Scotland, was the event’s first in-person occurrence since 2019, and it was exciting to be back – Edinburgh didn’t disappoint! There was rich dialogue amongst industry experts, healthy attendance with over 2,000 delegates, exceptional networking events, and the city of Edinburgh was a joy with several unseasonably sunny days.

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