Aldevron Breakthrough Blog: Cell Therapy

Aiming for improved delivery, safety, at ESGCT

Covering multiple modalities

Every year, October marks the change in the season, the dropping of temperatures, and the height of conference season for biotech. This year’s ESGCT meeting in Edinburgh, Scotland, was the event’s first in-person occurrence since 2019, and it was exciting to be back – Edinburgh didn’t disappoint! There was rich dialogue amongst industry experts, healthy attendance with over 2,000 delegates, exceptional networking events, and the city of Edinburgh was a joy with several unseasonably sunny days.

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Webinar: Genome Editing Tools: Beyond Discovery

CRISPR nucleases and NanoplasmidTM working together

As one of the most significant discoveries in gene and cell therapy, CRISPR/Cas9 genome editing systems continue to evolve. In this webinar, “Genome Editing Tools: Beyond Discovery,” Aldevron experts Dr. Jim Williams and Max Sellman detail innovative tools to support gene editing clinical programs, highlighting Nanoplasmids as an HDR template paired with Cas9 nucleases in CAR-T applications.

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Novel Stem Cell Therapies

A first look at patient data at ISSCR

I’m always grateful for the chance to hear the latest results from drug developers in the CRISPR space. That’s why it was a huge bonus to have a world class cell and gene therapy conference just fifteen minutes down the road from Aldevron Madison in September!

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Webinar on Demand: Advanced Plasmid Technology – Improving Safety and Performance

Nanoplasmid™ Vectors: The Power of Small

In cell and gene therapies, delivery is a critical factor. Regardless of your modality, optimizing payload, impact, and duration are common challenges. Countless programs, globally, are working on the delivery mechanism. However, many have overlooked a key component in improving therapeutic or manufacturing performance: the plasmid.

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The Benefits of Streamlining and Standardizing Plasmid DNA for Cell and Gene Therapies

Manufacturing standardization for cell and gene therapies (C&GT) has received increased focus in the last several years, spurred by the rapid exponential growth witnessed in this field. The resulting need for improved access to high-quality raw materials, including plasmid DNA, has made standardization integral to streamlining the development process for this biologic product category. 
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Aldevron Joins Cell and Gene Therapy Consortia

Cell and gene therapies (C&GTs) comprise a rapidly expanding segment of the life science industry. Due to this growth, companies can encounter significant challenges when scaling their therapeutics from research through clinical trials to commercialization.

The C&GT industry is working to standardize manufacturing processes and practices, and here at Aldevron we have joined forces with multiple industry consortia to help address these challenges.

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The Pivotal Role of Plasmid DNA

Plasmid DNA has historically been key to the development of biologic drug manufacturing. Today, it plays a critical role in the production of next-generation cell and gene therapies and vaccines. With our nearly 23 years of plasmid DNA manufacturing expertise, Aldevron has helped facilitate the advance of these important therapeutics. We continue to invest in additional capacity and novel capabilities to support biopharma manufacturers into the future.
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