Small-Scale. Big Impact.

July 30, 2025 by Deepika Bhargo

Empowering innovation with ssGMP

In the fast-paced world of genomic medicine, transformative therapies often begin with bold ideas, but not always with large-scale production needs. Early-stage innovators face numerous challenges, but accessing high-quality cGMP plasmid DNA should not be one of them. For those advancing early-phase programs, the need for reliable and scalable plasmid DNA at the right quantity is critical—and often underserved.

As part of our mission to be an engine of innovation for pioneers in genomic medicine, we recognize this growing demand among biotech startups, academic researchers, and early-stage drug developers for smaller, more agile, yet scalable solutions. These innovators do not need grams of plasmid DNA; they need just the right amount, delivered quickly and cost-effectively, without compromising quality.

Introducing ssGMP: Small-scale GMP Plasmid DNA
Our ssGMP service is purpose-built for clients who require smaller quantities of cGMP plasmid DNA—from 1 mg to 500 mg. It maintains the same high standards of quality and compliance as our large-scale offerings while bringing you these benefits:

• Flexible – Order only what you need, when you need it
• Fast – Accelerated timelines to keep your program on track
• Reliable – Backed by the same rigorous QC standards as our full-scale cGMP production

The size you need, when you need it
One of the greatest advantages of our ssGMP service is its right-sized platform manufacturing process. This ensures you receive exactly the amount of cGMP plasmid DNA your program requires. By eliminating unnecessary volume, we help reduce costs, minimize waste, and accelerate timelines, all while providing these advantages:

• Right-sized for early-phase trials
  Perfect for plasmids supporting small patient cohort clinical trials, AAV or lentivirus manufacturing, CRISPR-based gene editing, and transposon therapy
• Seamless scalability
  Start small with confidence, knowing you can transition smoothly to Aldevron’s traditional cGMP manufacturing as your program grows.
• Comprehensive quality control & quality assurance
  From upstream fermentation to downstream purification and stringent quality control assays, every step is meticulously managed to ensure exceptional quality.

Through our ssGMP service, you see an unwavering commitment to support innovation across the biotech development landscape. By making high-quality cGMP manufacturing more accessible and adaptable, you can be empowered to address the unmet needs of diverse therapeutic modalities now and into the future.

• Learn more on our ssGMP web page
• Have questions on this topic? Contact Us
• Have an idea for a topic? Let us know!

Subscribe to our blog