Aldevron Breakthrough Blog

The Pivotal Role of Plasmid DNA

Plasmid DNA has historically been key to the development of biologic drug manufacturing. Today, it plays a critical role in the production of next-generation cell and gene therapies and vaccines. With our nearly 23 years of plasmid DNA manufacturing expertise, Aldevron has helped facilitate the advance of these important therapeutics. We continue to invest in additional capacity and novel capabilities to support biopharma manufacturers into the future.


What's included in the The Pivotal Role of Plasmid DNA:

  • Plasmid DNA Overview
  • Benefits of Plasmid DNA
  • Manufacture of Vaccines and Gene Therapies
  • Gene Editing and Plasmid DNA
  • Advancing Plasmid Manufacturing at Aldevron

Download the Complete PDF


  1. Brown, James. “Supporting AAV and Lentiviral Vector Development and Commercialization.” Pharma’s Almanac. 24 May 2019.

About the author

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Robert Reames

Robert Reames

Robert Reames is Aldevron’s VP Global Technical Operations at the company’s Fargo, N.D., headquarters. Reames directs the company’s R&D and process development pipelines as well as overseeing research-grade nucleic acid manufacturing. He joined Aldevron in 2007, working in several roles throughout the company before achieving his director position.

Topics: Gene Editing, Cell Therapy, Gene Therapy, Plasmid DNA, Clinical Grade Manufacturing/cGMP, Client Experience, Research Grade Manufacturing, Research and Development, Vaccines