Aldevron Breakthrough Blog
CDMOs, Expertise and Experience
October 11, 2023 / by Basam Barkho, Ph.D.
Considering the processes of mRNA manufacturing
Similar to a comedian developing a stand-up routine around the latest trends, a Chief Scientific Officer (CSO) drives current methods and technologies for biological therapeutics. Both have insightful viewpoints of their trade, with the CSO closely working in the world of both academic and industrial research for development of drug products from conception to commercialization.
In the case of Contract Development and Manufacturing Organizations (CDMOs), it is like a car, very practical for getting you from one point to another. They are designed to be a reliable partner to (tech) transfer material for your company, allowing a streamlined process in your development programs.
For Venkata Indurthi, Ph.D., Aldevron’s CSO, he applied both of those approaches in his editorial article, “CSOs in CDMOs giving mRNA manufacturing considerations,” in the latest edition of International Biopharmaceutical Industry (IBI).
In mRNA drug product manufacturing, skill and experience are critical when planning, developing and executing the mRNA production from sequence to vial. Therefore, when designing mRNA drug products, it is important to note several considerations before moving forward.
It’s similar to making coffee, where the process is very critical, from bean to cup, to make the perfect brew. With the process of mRNA drug product manufacturing, each step has standard methods, but also has very practical knowledge and techniques to get the correct product.
With that, we invite you to grab a perfectly brewed cup of coffee and read the IBI editorial, “CSOs in CDMOs giving mRNA manufacturing considerations.” It provides the opportunity to learn more about standards and practical processes for mRNA drug product manufacturing, with Indurthi’s thoughts on the sector.
- Download CSOs in CDMOs giving mRNA manufacturing considerations [PDF]
- Have questions about this topic? Contact Venkata Indurthi
- Learn more about Aldevron's mRNA capabilities
- Have an idea for a topic? Let us know!
Basam Barkho, Ph.D.
Basam Barkho serves as a technical marketing manager for Aldevron’s marketing team. He earned a bachelor's degree in Molecular Biology from the University of California San Diego, and a Ph.D. in Neuroscience from Biomedical Science Program from the University of New Mexico in Albuquerque, NM. His Ph.D. training focused on understanding the intrinsic mechanisms of stem cells in response to injury or disease. Basam continued research in stem cell applications as a postdoc before joining Novartis Gene Therapies in San Diego to develop gene therapy programs and enhance the delivery system for rare diseases.