Aldevron Breakthrough Blog / Venkata Indurthi, Ph.D.

A Focus on Analytics, for RNA and Beyond

Driving innovation of industry tools

Analytical innovation is often overlooked in discussions of biotechnology product development and manufacturing processes. For example, in the DNA area, most “state of the art” analytical methods in use were developed in the 1980s, or even earlier. Industrywide, there is a need to continuously innovate in the analytical space due to the tremendous advances in enabling technologies.

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Comparing Capping

Enzymatic and co-transcriptional capping for RNA

With the manufacture of RNA, capping is one of the many crucial steps in developing the final product. There are two methods of capping, enzymatic and co-transcriptional. Both have advantages and disadvantages.

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A Three-Step RNA Progression

An outlook for mRNA, saRNA and Circular RNA

When mRNA vaccines began to roll out in late 2020 to fight the COVID pandemic, it was the first large-scale use of the molecule after years of research. But the success of those vaccines was only the beginning of new opportunities for the RNA field.

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