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November
2011
Burden CS et al (2011): A monolith purification process for virus-like particles from yeast homogenate. Journal of Chromatography B, doi:10.1016/j.jchromb.2011.10.044
November
2011
Hermann RJ et al (2011): Characterization and use of a rabbit-anti-mouse VPAC1 antibody by flow cytometry. Journal of Immunological Methods, doi:10.1016/j.jim.2011.10.009
October
2011
Weinberg A et al (2011): Science gone translational: the OX40 agonist story. Immunological Reviews 244/1: 218-231
August
2011
de Lau W et al (2011): Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476/293, doi:10.1038/ nature10337
June
2011
van Montfort T et al (2011): A Chimeric HIV-1 Envelope Glycoprotein Trimer with an Embedded Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Domain Induces Enhanced Antibody and T Cell Responses. JBC, 286, 22250-22261
May
2011
Niessner C et al (2011): Avian Ultraviolet/Violet Cones Identified as Probable Magnetoreceptors. PLoS One. 2011; 6(5): e20091.
April
2011
Brancaleone V et al (2011): Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature. JImmunol 186/8, 4905-4914
April
2011
Zaremba A, Schmuecker U and Esche H (2011): Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway.Virology Journal 2011, 8:192
March
2011
Porotto M et al (2011): Synthetic protocells interact with viral nanomachinery and inactivate pathogenic human virus. PLoS One. 2011; 6(3): e16874.
January
2011
Kuespert K et al (2011): Neisseria meningitidis has two independent modes of recognizing its human receptor CEACAM1. PLoS One. 2011; 6(1): e14609.
December
2010
Hutchings CJ et al (2010): Therapeutic antibodies directed at G protein-coupled receptors. mAbs 2/6, 594-606.
December
2010
Legrand F et al (2010): Human Eosinophils Exert TNF-α and Granzyme A-Mediated Tumoricidal Activity toward Colon Carcinoma Cells. JImmunol 185/12, 7443-7451
November
2010
Zeisel M et al (2010): Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. J Hepatol, doi:10.1016/j.jhep.2010.10.014
November
2010
De Santo C et al (2010): Invariant NKT cells modulate the suppressive activity of Serum Amyloid A-differentiated IL-10-secreting neutrophils. Nat Immunol.; 11(11): 1039–1046.
October
2010
Spurr L et al (2010): Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets. International Immunopharmacology, doi:10.1016/j.intimp.2010.10.006
October
2010
Rolhion N et al (2010): Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion. Gut, 59/10: 1355-6
October
2010
Weibel R et al (2010): Development of Standard Test Procedures for Quantifying Carry Over from Fixed Pipetting Tips in Liquid-Handling Systems. J Ass Lab Auto, 15/5: 369-378
October
2010
Iten M et al (2010): Reduction of Carry Over in Liquid-Handling Systems With a Decontamination Step Integrated in the Washing Procedure. J Ass Lab Auto, 15/5: 379-389
September
2010
Xianfeng Chen, Angela Shaulov Kask, et al (2010) Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays, Journal of Controlled Release, Volume 148, Issue 3, 20 December 2010, Pages 327-333, ISSN 0168-3659, DOI: 10.1016/j.jconrel.2010.09.001.
September
2010
VanDuijn M et al (2010): Immune Responses Are Characterized by Specific Shared Immunoglobulin Peptides That Can Be Detected by Proteomic Techniques. JBC 285, 29247-29253.
September
2010
Fofana I et al (2010): Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastoenterology (10.1053/j.gastro.2010.05.073).
September
2010
Angela Shaulov Kask, Xianfeng Chen, et al (2010): DNA vaccine delivery by densely-packed and short microprojection arrays to skin protects against vaginal HSV-2 challenge, Vaccine, Volume 28, Issue 47, 3 November 2010, Pages 7483-7491, ISSN 0264-410X, DOI: 10.1016/j.vaccine.2010.09.014.
August
2010
Kanderova V et al (2010): Aberrantly expressed CEACAM6 is involved in the signaling leading to apoptosis of acute lymphoblastic leukemia cells. Exp Hem 38/8, 653-660.
July
2010
Ha CT et al (2010): Human Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Has a Potential Role in Placental Vascular Morphogenesis. Biol Reprod.; 83(1): 27–35
June
2010
Ortner E et al (2010): Sensitive and selective detection of free FXIII activation peptide: a potential marker of acute thrombotic events. Blood 115/24, 5089-5096
April
2010
Krieger SE et al (2010): Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-Claudin-1 associates. Hepatology, 51/4:1144-57
April
2010
Betts AM et al (2010): The Application of Target Information and Preclinical Pharmacokinetic/Pharmacodynamic Modeling in Predicting Clinical Doses of a Dickkopf-1 Antibody for Osteoporosis. JPet, 333/1, 2-13
March
2010
Abrami L et al (2010): Endocytosis of the Anthrax toxin is mediated by Clathrin, Actin and unconventional adaptors. PLoS Pathog. 2010 March; 6(3): e1000792.
January
2010
Singer B et al (2010): Deregulation of the CEACAM Expression Pattern Causes Undifferentiated Cell Growth in Human Lung Adenocarcinoma Cells. PLoS One. 2010; 5(1): e8747
September
2009
Carvalho, FA et al (2009): Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM. JEM, 206/10: 2179-2189.
August
2009
Gross JC et al (2009): E-cadherin Surface Levels in Epithelial Growth Factor-stimulated Cells Depend on Adherens Junction Protein Shrew-1. MBoC 20/15: 3598-3607
July
2009
Yue T et al (2009): The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. Mol Cell Proteomics. 8(7): 1697-707.
July
2009
Bratke et al (2009): Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4+ T cells by down-regulation of granzyme B. Immunology. 127/3: 338–344
July
2009
Adler H et al (2009): Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1. PLoS ONE 4/7
May
2009
Porotto M et al (2009): Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy. J Virol., 83(10): 5148-55.
May
2009
Martins V et al (2009): ATLa, an Aspirin-Triggered Lipoxin A4 Synthetic Analog, Prevents the Inflammatory and Fibrotic Effects of Bleomycin-Induced Pulmonary Fibrosis. J Immunol, 182: 5374 -5381
May
2009
Kang H et al (2009): Transfection of insulin-secreting cell line and rat islets by functional polymeric gene vector. Biomaterials, 30/14: 2837-2845
March
2009
Taori V et al (2009): DNA delivery in vitro via surface release from multilayer assemblies with poly(glycoamidoamine)s. Acta Biomaterialia, 5/3: 925-933
March
2009
Han Y et al (2009): Using DNA as drug-bioprocessing and delivery strategies. Chemical Engineering Research and Design, 87/3: 343-348
March
2009
Latulippe D et al (2009): Elongational flow model for transmission of supercoiled plasmid DNA during membrane ultrafiltration. Journal of Membrane Science, 329/1: 201-208
February
2009
Teijeiro-Osorio D et al (2009): Chitosan/cyclodextrin nanoparticles can efficiently transfect the airway epithelium in vitro. Eur J Pharm Biopharm, 71/2: 257-263
February
2009
Srinivasachari S et al (2009): Versatile supramolecular pDNA vehicles via "click polymerization" of beta-cyclodextrin with oligoethyleneamines. Biomaterials, 30/5: 928-938
February
2009
Semiramoth N et al (2009): Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase -and MAPK- dependent mechanism. J Leukocyte Biol, 85, 1-12
January
2009
Guignot J et al. (2009): Human decay-accelerating factor and CEACAM receptor-mediated internalization and intracellular lifestyle of Afa/Dr diffusely adhering escherichia coli in epithelial cells. Infection and Immunity, 77/1, 517-531
December
2008
Polymenidou M et al. (2008): The POM Monoclonals: A comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS ONE ; 3/12: e3872.
December
2008
Porada CD et al (2008): Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells. Exp Hematol, 36/12: 1739-1749
November
2008
Hooper JW, et al (2008): Immune serum produced by DNA vaccination protects hamsters against lethal respiratory challenge with Andes virus. FJ Virol., 82(3):1332-8.
November
2008
Beaslas O et al (2008): Transcriptome response of enterocytes to dietary lipids: impact on cell architecture, signaling, and metabolism genes. Am J Physiol Gastrointest Liver Physiol, 295/5: G942-52
July
2008
Paulmann D et al. (2008): Hepatitis A virus protein 2B suppresses beta interferon (IFN) gene transcription by interfering with IFN regulatory factor 3 activation. J Gen Virol 89, 1593-1604
June
2008
Thomas SN et al. (2008): Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow. J Biol Chem, 283: 15647-55.
June
2008
Planaguama A et al (2008): Airway Lipoxin A4 Generation and Lipoxin A4 Receptor Expression Are Decreased in Severe Asthma. Am J Respir Crit Care Med, 178a: 574-582
May
2008
Lee HSW et al (2008): CEACAM1 Dynamics during Neisseria gonorrhoeae Suppression of CD4+ T Lymphocyte Activation. J Immunol, 180: 6827-6835
February
2008
Dalley D et al (2008): Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles). Tuberculosis 88/3: 235-243, doi:10.1016/j.tube.2007.11.001
February
2008
Björkman L et al (2008): Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1. J Leukoc Biol, 83: 245-53
December
2007
Yoon J et al (2007): CD66b regulates adhesion and activation of human eosinophils. J Immunol, 179: 8454-62
December
2007
Zeisel M et al. (2007): Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology, 46/6:1722-31
December
2007
Riesenberg R et al (2007): Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma. Clin Cancer Res, 13/23, 6993-7002
December
2007
Kilic N et al (2007): Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1. Blood, 110/13, 4223-4233
August
2007
Schmitter T et al (2007): Opa proteins of pathogenic neisseriae initiate Src kinase-dependent or lipid raft-mediated uptake via distinct human carcinoembryonic antigen-related cell adhesion molecule isoforms. Infect Immun, 75/8:4116-26.
June
2007
Bonn S et al (2007): Combinatorial expression of α- and γ-protocadherins alters their presenilin-dependent processing. Mol Cell Biol, 27/11: 4121-4132
May
2007
Morris NP et al (2007): Development and characterization of recombinant human Fc:OX40L fusion protein linked via a coiled-coil trimerization domain. Mol Immunol 44/12: 3112-3121
May
2007
Catanese MT et al. (2007): High avidity monoclonal antibodies against human scavenger receptor class B type I efficiently block hepatitis C virus infection in the presence of HDL. J Virol, 2007 0: JVI.00193-07
April
2007
Schreiner A et al. (2007): Junction protein Shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147. Mol Biol Cell, 18/4:1272-81
March
2007
Vicovac L et al (2007):Carcinoembryonic Antigen and Related Molecules in Normal and Transformed Trophoblast. Placenta 28/2-3:85-96, doi:10.1016/j.placenta.2006.02.002
February
2007
Chan CHF et al. (2007): Colorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice. PLoS ONE, 2/12: e1353
January
2007
Viswanathan A et al. (2007): Functional expression of N-formyl peptide receptors in human bone marrow-derived mesenchymal stem cells. Stem Cells, 25/5:1263-9
December
2006
Weinberg AD et al. (2006): Anti-OX40 (CD134) Administration to nonhuman primates: immunostimulatory effects and toxicokinetic study. J Immunother, 29/6: 575-585
November
2006
Ellies D et al. (2006): Bone density ligand, sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res, 21/11:1738-49
October
2006
D'Amour K et al (2006): Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol, 24/1: 1392-1401
September
2006
Maraqa L. et al (2006): CEACAM: A potential novel predictor of breast cancer recurrence. AACR Meeting Abstracts 2006 : PR-8
September
2006
Technology Feature: 'Chain gang' delivers for hard labor. Nature Methods, 3/9: 753-762
May
2006
Tsutsumida H et al (2006): RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells. Clin Cancer Res, 12: 2976-87
April
2006
Krause S et al. (2006): Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor _1. Mol Immunol, 33/11: 1799-1807
April
2006
Avadhanula V et al. (2006): Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol, 80/4: 1629-1636
March
2006
Nöckel J et al (2006): Characterization of gastric adenocarcinoma cell lines established from CEA424/SV40 T antigen-transgenic mice with or without a human CEA transgene. BMC Cancer, 6: 57
February
2006
Pavoni E et al. (2006): Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein. BMC Cancer, 6: 41
November
2005
Klaile E et al (2005): CEACAM1 functionally interacts with filamin A and exerts a dual role in the regulation of cell migration. JCS, 118: 5513-5524
November
2005
Bade B et al (2005): Differential expression of the granzymes A, B, K, M and perforin in human peripheral blood lymphocytes. Int. Immunol, 17: 1419-1428
October
2005
D'Amour K et al. (2005): Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol, 23: 1534-1541
October
2005
Bratke K et al (2005): Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood. Eur J Immunol, 35/9: 2608-2616
October
2005
Bade B et al. (2005): Detection of soluble human granzyme K in vitro and in vivo. Eur J Immunol, 35/10:2940-2948
September
2005
Roessler et al (2005): Identification of Nicotinamide N-Methyltransferase as a novel serum tumor marker for colorectal cancer. Clin Cancer Res, 11/18: 6550-6558
August
2005
Muenzner P et al (2005): CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol, 170/5: 825-836
May
2005
Neckermann S et al (2005): Presentation of the human Hepatitis B surface antigen–loop by the Cpn10 scaffold induces a specific antibody response in mice by genetic immunization. FOCiS annual meeting, Boston, Poster F2.39.
April
2005
Kalina T et al (2005): Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens. BMC Cancer 5: 38
April
2005
Kunii R et al. (2005): Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13. J Periodontal Res, 40/2:138-46
December
2004
Nanda A et al. (2004): Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Res, 64: 8507-8511
October
2004
Kammerer R et al. (2004): The tumour suppressor gene CEACAM1 is completely but reversibly downregulated in renal cell carcinoma. J Pathol, 204/3: 258-267.
September
2004
Haynes C and BS Schnierle (2004): Retroviral vector targeting through insertion of epidermal growth factor into receptor binding deficient influenza A hemagglutinin results in fusion defective particles. J Virol Methods, 120/2: 189-199
September
2004
Kiessling J et al. (2004): Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm. EMBO reports 5 /9: 889-894
August
2004
Myrtek D et al. (2004): Expression of interleukin-13 receptor a 1-subunit on peripheral blood eosinophils is regulated by cytokines. Immunology, 112: 597-604
May
2004
McCaw S et al. (2004): Engulfment of Neisseria gonorrhoeae: Revealing distinct processes of bacterial entry by individual carcinoembryonic antigen-related cellular adhesion molecule family receptors. Infection and Immunity, 72/5: 2742-2752
January
2004
Schmitter T et al. (2004): Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med, 199/1: 35-46.
January
2004
Hakansson P et al (2004): Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a). Leukemia 18, 538–547
January
2004
Elagoz A et al. (2004): A truncated form of CKb8-1 is a potent agonist for human formyl peptide-receptor-like 1 receptor. Br J Pharmacol, 141/1: 37-46.
January
2004
Bharti S (2004): Novel membrane protein shrew-1 targets to Cadherin-mediated junctions in polarized epithelial cells. Mol Biol Cell, 15: 397-406.
December
2003
Fahlgren A et al. (2003): Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. Scand J Immunol, 58/6:628-641.
November
2003
de Jonge MI et al. (2003): Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors. Mol Microbiol, 50/3: 1005
October
2003
A shortcut from genomics to drug development. By Jens Lohrmann, Stefan Lang and John Thompson, published in Current Drug Discovery, October 2003. (For reprints please contact Dr. Stefan Lang.)
May
2003
de Jonge MI et al. (2003): Functional activity of antibodies against the recombinant OpaJ protein from Neisseria meningitides. Infection and Immunity, 71/5:2331-2340
February
2003
Custom-made antibodies produced by genetic immunisation: Applications in drug development, therapy and diagnosis. By Stefan Lang and John Thompson, published in Global Outsourcing Review, Vol. 5, No. 1, Spring 2003. (For reprints please contact Dr. Stefan Lang.)
December
2002
Genetische Immunisierung zur Antikörperproduktion. Von Stefan Lang und John Thompson, veröffentlicht in transkript, 12/02, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.)
October
2002
Bioprocessing - Genetic Immunization for Antibody Production. Tutorial: Genovac's Technological Shortcut From Gene to Antibody. By John Thompson, Ph.D., and Stefan Lang, Ph.D., published in Genetic Engineering News, Vol. 22, No. 17, October 1, 2002 (For reprints please contact Dr. Stefan Lang.)
October
2002
Klippel S et al. (2002): Biochemical characterisation of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera. Blood, 100/7: 2441-2448
September
2002
Genetische Immunisierung - ein hocheffizientes Verfahren zur Antikörper-Herstellung für die medizinische Diagnostik und Therapie. Von Stefan Lang und John Thompson, veröffentlicht in BIOspektrum, Sonderausgabe Proteomics & Drug Development, 8.Jahrgang. (Text only in German. For reprints please contact Dr. Stefan Lang.)
August
2002
Bioprocessing - Capacity mismatch for production of monoclonals: Development-stage enhancements alleviate bottleneck. By Angelo DePalma, Ph.D., published in Genetic Engineering News, Vol. 22, No. 14, August 2002 (For reprints please contact Dr. Stefan Lang.)
April
2002
Billker O et al. (2002): Distinct mechanisms of internalisation of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Pac1- and Cdc42-dependent and independent pathways. EMBO J, 21/4: 560-571
March
2002
Boulton IC and SD Gray-Owen (2002): Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes. Nat Immunol, 3/3:229-236
September
2001
Watt SM et al. (2001): Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site. Blood, 98/5: 1469-1479
September
2001
Richter G. et al. (2001): Tumor necrosis factor -alpha regulates the expression of ICOS ligand on CD34+ progenitor cells during differentiation into antigen presenting cells. J Biol Chem, 276/49: 45686-93
April
2000
Temerinac S et al. (2000): Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. Blood, 95/8: 2569-2576
February
2000
Schoelzel S et al. (2000): Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol, 156/2: 595-605