pALD-X80 for rAAV Production

Ready-to-use rAAV helper plasmid

Triple transfection is the most common method for rAAV production and does not require co-infection with adenovirus, a helper plasmid provides adenoviral genes. Aldevron's pALD-X80 has several advantages.

  • pALD-X80 MapReplaces any existing pAdDeltaF6 (pHelper) or pXX6-80 plasmid
  • Immediately available
  • Based on pXX6-80 used to produce rAAV for dozens of clinical trials
  • Kanamycin resistance, an alternative to ampicillin acceptable to regulatory agencies 

With Aldevron's pALD-X80, clients do not need to manufacture a custom batch of the helper plasmid. It can be purchased as an off-the-shelf product, reducing timeline and cost. We also provide pALD-X80 free of charge for research applications (quantities limited).

A solution from early research through commercial development
pALD-X80 is available in three quality grades: Research, GMP-SourceTM and GMP. Clients have the option of choosing the quality grade that fits their needs and stage of development with the assurance that the royalty-free product will be available when it's needed.

Learn more about pALD-X80 and request a free sample

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