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Plasmids for Vaccine Validation
pCMV-S (also known as pRc/CMV-HBs) is widely used to validate DNA vaccine delivery and formulation strategies. This plasmid expresses the hepatitis B surface antigen (HBsAg) under the control of the CMV immediate-early promoter.
pCMVHB-S2.S expresses the small and middle forms of recombinant HBsAg. The plasmid can be used to generate anti-HBsAg antibodies like pCMV-S. It is also used to fuse other sequences to the S form of HBsAg.
The antibody response to pCMV-S and/or pCMVHB-S2.S can be tested via ELISA using Aldevron's recombinant HBsAg. Both of these plasmids are available free of charge for research applications. These vectors are covered and described by United States Patent 6,635,624 which is available at www.uspto.gov.
Plasmids for validating DNA vaccine delivery and formulation.
| Description | Cat # | Price | Order |
|---|---|---|---|
|
pCMV-S (pRC/CMV-HBs) MAP SEQUENCE *Free Sample limited to 1 per person |
5012FS 5012 |
FREE ≈ 2 µg - 10 mg |
|
|
pCMVHB-S2.S MAP SEQUENCE *Free Sample limited to 1 per person |
5013FS 5013 |
FREE ≈ 2 µg - 10 mg |
|
|
HBsAg (recombinant, ayw subtype) QUANTITY PRICING |
5014 5014.0100 5014.0050 |
- 1 mg - 100 µg - 50 µg |
|
|
HBsAg (recombinant, adw subtype) QUANTITY PRICING |
5015 5015.0100 5015.0050 |
- 1 mg - 100 µg - 50 µg |
|
Overview
Aldevron manufactures high-quality plasmids, proteins, and antibodies for a variety of applications. Most of these have been developed and/or produced with the same technology used in our contract services. Aldevron reagents are generally ready-to-ship, and delivered within 24 hours.