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sNLS-SpCas9-sNLS Nuclease

A simple solution from R&D to clinical material

Aldevron provides research grade Cas9 nucleases for use in development work as well as standard GMP products for clinical studies. The concentration for these products is 10 mg/mL, dispensed in the following sizes:

ald-cas9-rg-gmp

Functional Performance

Manufacturing and Quality Control

Download CoAs to See QC Specifications

To download your CoAs, please provide your contact information below. We do not share your information with any third parties.

sNLS-SpCas9-sNLS Nuclease Quality Control Specifications
Purity, RP-HPLC ≥95%
Purity, SDS-PAGE ≥95%
Aggregation ≤5% aggregate
Concentration 10.0 mg/mL +/- 10%
Endotoxin ≤ 10 EU/mg
Residual DNase < LOQ
Residual RNase < LOQ
Appearance Clear, colorless
Residual Host Protein ≤ 200 ng/mL
Residual Host GenomicDNA < 1% (w/w)
Activity Assay, in vitro ≥80% of uncut reference DNA converted to cleavage products
Bioburden < 2 CFU/Sample
Mycoplasma Negative for the presence of Mycoplasma

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Ordering Information

Product Small Size Catalog Number Large Sizes Catalog Number
SpCas9 Nuclease 0.25MG 9212-0.25MG 5MG 9212-5MG
GMP-Manufactured Nucleases
SpCas9 Nuclease - GMP 1MG 9211-0.1ML 10MG 9211-1ML

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