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GIA: Genetic Immunization and Antibody Production  
Genetic Immunization and Antibody Production
Your solution for DNA vaccine screening and DNA-based antibody generation.

Rapidly test DNA vaccines at Aldevron
Aldevron's GIA™ service combines genetic immunization with a proprietary DNA delivery technology for rapidly generating antibodies to any gene-specific antigen. Our patented immunization system has been shown to enhance the response to DNA vaccines by over 100-fold in mice, rats, rabbits, and larger animal models. This makes GIA ideal for screening DNA vaccines at Aldevron. Simply send your plasmids to Aldevron and we will supply you with the immunized animal sera.

Antibody generation
GIA also offers many advantages over conventional antibody generation. There is no need for recombinant or synthetic antigens, the antibodies exhibit a higher affinity to the target protein, and the development time is greatly reduced. Maximum titers have been reached in as little as 28 days using GIA technology.

  • Rapidly screen DNA Vaccine candidates
  • Generate high affinity antibodies without recombinant proteins
  • Over 100-fold greater antibody response than conventional immunization protocols
  • United States Patent #s 6,110,161; 6,621,281; and 6,610,044

Download a pdf information sheet for this service

elgen™Next generation immunization technology for vaccine development and antibody production using elgen™ gene delivery technology.

Choices
Aldevron can use your plasmid or we can construct one for you. Also, we offer over 40 gene therapy and DNA vaccine plasmids encoding cytokines, reporter proteins, and therapeutic enzymes. Any of these can be used with GIA. Aldevron will use our immunization methods or we can work with you to develop project specific protocols, customizing a study schedule to fit your needs.

Contact
Aldevron will use our immunization methods or we will work with you to develop project-specific protocols. We will customize a study schedule to fit your needs. For more details or to obtain pricing information, please contact us.