pRc/CMV-HBs(S)
Expresses the hepatitis B surface antigen
(small, or S, protein) under the control of the CMV immediate-early
promoter. This plasmid is available upon request for validating
DNA-based immunization methods and other experimental uses. The
antibody response to pCMV-S can be tested via ELISA with Aldevron's Recombinant
HBsAg. For further information, see the detailed
description of the plasmid.
pCMVHB-S2.S
Expresses the small and middle forms of Recombinant
HBsAg. Can be used to generate anti-HBsAg antibodies like pCMV-S.
Also can be used to fuse other sequences to the S form of HBsAg.
Excellent for validating new DNA vaccine delivery strategies. The
antibody response to pCMV-M can be tested via ELISA with Aldevron's
recombinant HBsAg. For more information, see the detailed description
of this plasmid.
These plasmids are covered and described by
United States Patent 6,635,624.
This is available online at http://www.uspto.gov.
By submitting the request for a free sample via our contact page,
you signify your agreement with the
following statement(s):
pRc/CMV-HBs(S):
I understand that the description of this
plasmid
is contained
in a patent application. I agree that it is to be used for research
purposes only, and that it is not to be used for any human experimentation.
I am aware that this plasmid has been described in Davis, H.L.,
Michel, M.L. & Whalen, R.G.
(1993)
DNA-based immunization
for hepatitis B induces continuous secretion of antigen and high
levels of circulating antibody. Human Molecular Genetics 2: 1847-1851.
I will endeavor to cite this paper where appropriate.
pCMVHB-S2.S:
I understand that the description of this
plasmid is contained in a patent application. I agree that it
is to be used for research purposes only, and that it is not
to be used for any human experimentation. I am aware that this
plasmid has been described in Michel ML, Davis HL, Schleef M,
Mancini M, Tiollais P, Whalen RG. DNA-mediated immunization to
the hepatitis B surface antigen in mice: aspects of the humoral
response mimic hepatitis B viral infection in humans. Proc Natl
Acad Sci USA. 1995 Jun 6; 92 (12): 5307-11. I will endeavor to
cite this paper where appropriate.
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