Genetic Immunization and Antibody Production (GIA)
Your
solution for DNA vaccine screening and
DNA-based antibody generation.
Rapidly test DNA vaccines at Aldevron
Aldevron's GIA™ service combines genetic immunization with a
proprietary DNA delivery technology for rapidly generating antibodies
to any gene-specific antigen. Our patented immunization system has
been shown to enhance the response to DNA vaccines by over 100-fold
in mice, rats, rabbits, and larger animal models. This makes GIA ideal
for screening DNA vaccines at Aldevron. Simply send your plasmids to
Aldevron and we will supply you with the immunized animal sera.
Antibody generation
GIA also offers many advantages over
conventional antibody generation.
There is no need for recombinant or synthetic antigens, the antibodies
exhibit a higher affinity to the target protein, and the development
time is greatly reduced. Maximum titers have been reached in as little
as 28 days using GIA technology.
- Rapidly screen DNA Vaccine candidates
- Generate high affinity antibodies
without recombinant proteins
- Over
100-fold greater antibody response
than conventional immunization protocols
- United
States Patent #s 6,110,161; 6,261,281;
and 6,610,044
Download a pdf information sheet for this service
Next
generation immunization technology for vaccine development and antibody
production using elgen™ gene
delivery technology.
Choices
Aldevron can use your plasmid or we can
construct one for you. Also, we offer over 40 gene therapy and DNA
vaccine plasmids encoding cytokines, reporter proteins, and therapeutic
enzymes. Any of these can be used with GIA. Aldevron will use our
immunization methods or we can work with you to develop project specific
protocols, customizing a study schedule to fit your needs.
Contact
Aldevron will use our immunization methods
or we will work with you to develop
project-specific protocols. We will
customize a study schedule to fit your needs. For more details or
to obtain pricing information, please contact
us. |
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